The BET Inhibitor OTX015 Exhibits In Vitro and In Vivo Antitumor Activity in Pediatric Ependymoma Stem Cell Models

by Tiziana Servidei, Daniela Meco, Maurizio Martini, Alessandra Battaglia, Alessia Granitto, Alexia Buzzonetti, Gabriele Babini, Luca Massimi, Gianpiero Tamburrini, Giovanni Scambia, Antonio Ruggiero, Riccardo Riccardi
Published 2021-02-01

CN133, a Novel Brain-Penetrating Histone Deacetylase Inhibitor, Hampers Tumor Growth in Patient-Derived Pediatric Posterior Fossa Ependymoma

by Roberta Antonelli, Carlos Jiménez, Misha Riley, Tiziana Servidei, Riccardo Riccardi, Aroa Soriano, Josep Roma, Elena Martínez-Saez, Maurizio Martini, Antonio Ruggiero, Lucas Moreno, Josep Sánchez de Toledo, Soledad Gallego, Jordi Bové, Jacob M. Hooker, Miguel F. Segura
Published 2020-07-01

Epigenetic Silencing of DKK3 in Medulloblastoma

by André Oberthuer, Giuseppe Cinalli, Tiziana Servidei, Massimo Zollo, Thomas Hielscher, Massimo Romani, Claudio Brigati, Alfa H.C. Bai, Marc Remke, Marcel Kool, Stefano Moretti, Stefan M. Pfister, Sara Stigliani, Barbara Banelli, Francesca Valdora, Gian Paolo Tonini, Simona Coco
Published 2013-04-01