Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking

by Megan M. Young, Yoshinori Takahashi, Todd E. Fox, Jong K. Yun, Mark Kester, Hong-Gang Wang
Published 2016-11-01

Use of high performance liquid chromatography-electrospray ionization-tandem mass spectrometry for the analysis of ceramide-1-phosphate levels[S]

by Dayanjan S. Wijesinghe, Jeremy C. Allegood, Luciana B. Gentile, Todd E. Fox, Mark Kester, Charles E. Chalfant
Published 2010-03-01

Altered Sphingolipid Metabolism in Patients with Metastatic Pancreatic Cancer

by Todd E. Fox, Mark Kester, Timothy M. Ritty, Yixing Jiang, Nicole A. DiVittore, Megan M Young, Zhiliang Jia, Keping Xie
Published 2013-07-01

Role of SPTSSB-Regulated de Novo Sphingolipid Synthesis in Prostate Cancer Depends on Androgen Receptor Signaling

by Pedro Costa-Pinheiro, Abigail Heher, Michael H. Raymond, Kasey Jividen, Jeremy JP. Shaw, Bryce M. Paschal, Susan J. Walker, Todd E. Fox, Mark Kester
Published 2020-12-01

Childhood growth and neurocognition are associated with distinct sets of metabolitesResearch in context

by G. Brett Moreau, Girija Ramakrishnan, Heather L. Cook, Todd E. Fox, Uma Nayak, Jennie Z. Ma, E. Ross Colgate, Beth D. Kirkpatrick, Rashidul Haque, William A. Petri, Jr
Published 2019-06-01

Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations

by Kristine C. Olson, Katharine B. Moosic, Marieke K. Jones, Paige M. K. Larkin, Thomas L. Olson, Mariella F. Toro, Todd E. Fox, David J. Feith, Thomas P. Loughran Jr
Published 2020-09-01

Circulating sphingolipid biomarkers in models of type 1 diabetes

by Todd E. Fox, Maria C. Bewley, Kellee A. Unrath, Michelle M. Pedersen, Robert E. Anderson, Dae Young Jung, Leonard S. Jefferson, Jason K. Kim, Sarah K. Bronson, John M. Flanagan, Mark Kester
Published 2011-03-01

Glucosylceramide synthase maintains influenza virus entry and infection.

by Kelly Drews, Michael P Calgi, William Casey Harrison, Camille M Drews, Pedro Costa-Pinheiro, Jeremy Joseph Porter Shaw, Kendra A Jobe, John D Han, Todd E Fox, Judith M White, Mark Kester
Published 2020-01-01

Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation

by Su-Fern Tan, Wendy Dunton, Xin Liu, Todd E. Fox, Samy A.F. Morad, Dhimant Desai, Kenichiro Doi, Mark R. Conaway, Shantu Amin, David F. Claxton, Hong-Gang Wang, Mark Kester, Myles C. Cabot, David J. Feith, Thomas P. Loughran, Jr.
Published 2019-06-01

C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia.

by Lindsay K Ryland, Ushma A Doshi, Sriram S Shanmugavelandy, Todd E Fox, Cesar Aliaga, Kathleen Broeg, Kendall Thomas Baab, Megan Young, Osman Khan, Jeremy K Haakenson, Nancy Ruth Jarbadan, Jason Liao, Hong-Gang Wang, David J Feith, Thomas P Loughran, Xin Liu, Mark Kester
Published 2013-01-01

SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models

by Jeremy A Hengst, Taryn E Dick, Arati Sharma, Kenichiro Doi, Shailaja Hegde, Su-Fern Tan, Laura M Geffert, Todd E Fox, Arun K Sharma, Dhimant Desai, Shantu Amin, Mark Kester, Thomas P Loughran, Robert F Paulson, David F Claxton, Hong-Gang Wang, Jong K Yun
Published 2017-01-01

Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia1

by Samy A.F. Morad, Terence E. Ryan, P. Darrell Neufer, Tonya N. Zeczycki, Traci S. Davis, Matthew R. MacDougall, Todd E. Fox, Su-Fern Tan, David J. Feith, Thomas P. Loughran, Jr., Mark Kester, David F. Claxton, Brian M. Barth, Tye G. Deering, Myles C. Cabot
Published 2016-07-01

Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells

by Li-Pin Kao, Samy A.F. Morad, Traci S. Davis, Matthew R. MacDougall, Miki Kassai, Noha Abdelmageed, Todd E. Fox, Mark Kester, Thomas P. Loughran, Jr., Jose' L. Abad, Gemma Fabrias, Su-Fern Tan, David J. Feith, David F. Claxton, Sarah Spiegel, Kelsey H. Fisher-Wellman, Myles C. Cabot
Published 2019-09-01