New prospects for incretin‐related drugs in the treatment of type 2 diabetes

by Tomohiko Kimura, Kohei Kaku
Published 2021-07-01

Inhibition and Facilitation by Pimobendan, a Calcium Sensitizer, of Catecholamine Secretion From Bovine Adrenal Chromaffin Cells

by Haruhiro Kuwashima, Chiaki Matsumura, Tomohiko Kimura
Published 2003-01-01

Inhibition by SEA0400, a Selective Inhibitor of Na+/Ca2+ Exchanger, of Na+-Dependent Ca2+ Uptake and Catecholamine Release in Bovine Adrenal Chromaffin Cells

by Shin Soma, Haruhiro Kuwashima, Chiaki Matsumura, Tomohiko Kimura
Published 2006-01-01

Multifaceted Mechanisms of Action of Metformin Which Have Been Unraveled One after Another in the Long History

by Hideaki Kaneto, Tomohiko Kimura, Atsushi Obata, Masashi Shimoda, Kohei Kaku
Published 2021-03-01

Unexpected Pleiotropic Effects of SGLT2 Inhibitors: Pearls and Pitfalls of This Novel Antidiabetic Class

by Hideaki Kaneto, Atsushi Obata, Tomohiko Kimura, Masashi Shimoda, Tomoe Kinoshita, Taka-aki Matsuoka, Kohei Kaku
Published 2021-03-01

Favorable Effects of GLP-1 Receptor Agonist against Pancreatic β-Cell Glucose Toxicity and the Development of Arteriosclerosis: “The Earlier, the Better” in Therapy with Incretin-B...

by Hideaki Kaneto, Tomohiko Kimura, Masashi Shimoda, Atsushi Obata, Junpei Sanada, Yoshiro Fushimi, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku
Published 2021-07-01

Notable Underlying Mechanism for Pancreatic β-Cell Dysfunction and Atherosclerosis: Pleiotropic Roles of Incretin and Insulin Signaling

by Hideaki Kaneto, Atsushi Obata, Tomohiko Kimura, Masashi Shimoda, Junpei Sanada, Yoshiro Fushimi, Naoto Katakami, Takaaki Matsuoka, Kohei Kaku
Published 2020-12-01

Case Report: Malignant Pheochromocytoma Without Hypertension Accompanied by Increment of Serum VEGF Level and Catecholamine Cardiomyopathy

by Hideaki Kaneto, Shinji Kamei, Fuminori Tatsumi, Masashi Shimoda, Tomohiko Kimura, Shuhei Nakanishi, Yoshiyuki Miyaji, Atsushi Nagai, Kohei Kaku, Tomoatsu Mune
Published 2021-06-01

Multiple endocrine neoplasia type 1 with a frameshift mutation in its gene accompanied by a giant cervical lipoma and multiple fatty deposits in the pancreas: case report

by Yoshiro Fushimi, Shinji Kamei, Fuminori Tatsumi, Junpei Sanada, Masashi Shimoda, Tomohiko Kimura, Atsushi Obata, Shuhei Nakanishi, Kohei Kaku, Tomoatsu Mune, Hideaki Kaneto
Published 2021-08-01

Administration of RAS Inhibitor before the Onset of Diabetic Nephropathy Counteracts the Adverse Effect of Chronic Hyperglycemia and Reduces the Augmentation of Urinary Albumin Exc...

by Hidenori Hirukawa, Shinji Kamei, Tomohiko Kimura, Atsushi Obata, Kenji Kohara, Fuminori Tatsumi, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Published 2018-01-01

Idiopathic Bilateral Extraocular Myositis in a Subject With Poorly Controlled Type 2 Diabetes Mellitus: Case Report

by Fuminori Tatsumi, Yoshiro Fushimi, Junpei Sanada, Masashi Shimoda, Kenji Kohara, Tomohiko Kimura, Atsushi Obata, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Published 2021-09-01

A case of tamoxifen-induced hypertriglyceridemia monitoring the changes in lipoprotein fractions over time

by Hayato Isobe, Masashi Shimoda, Yuki Kan, Fuminori Tatsumi, Yukino Katakura, Tomohiko Kimura, Atsushi Obata, Kenji Kohara, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Published 2021-06-01

Inadequate Triglyceride Management Worsens the Durability of Dipeptidyl Peptidase-4 Inhibitor in Subjects with Type 2 Diabetes Mellitus

by Masashi Shimoda, Maiko Miyoshi-Takai, Shintaro Irie, Akihito Tanabe, Atsushi Obata, Seizo Okauchi, Hidenori Hirukawa, Tomohiko Kimura, Kenji Kohara, Shinji Kamei, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Published 2017-01-01

Effect of Tofogliflozin on Body Composition and Glycemic Control in Japanese Subjects with Type 2 Diabetes Mellitus

by Shinji Kamei, Masahiro Iwamoto, Miyuki Kameyama, Masashi Shimoda, Tomoe Kinoshita, Atsushi Obata, Tomohiko Kimura, Hidenori Hirukawa, Fuminori Tatsumi, Kenji Kohara, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Published 2018-01-01

Switching From Daily DPP-4 Inhibitor to Once-Weekly GLP-1 Receptor Activator Dulaglutide Significantly Ameliorates Glycemic Control in Subjects With Poorly Controlled Type 2 Diabet...

by Junpei Sanada, Tomohiko Kimura, Masashi Shimoda, Akiko Tomita, Yoshiro Fushimi, Tomoe Kinoshita, Atsushi Obata, Seizo Okauchi, Hidenori Hirukawa, Kenji Kohara, Fuminori Tatsumi, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Published 2021-08-01

Verification of Kumamoto Declaration 2013 and Glycemic Targets for Elderly Patients with Diabetes in Japan for prevention of diabetic complications: A retrospective longitudinal st...

by Shuhei Nakanishi, Hidenori Hirukawa, Masashi Shimoda, Fuminori Tatsumi, Kenji Kohara, Atsushi Obata, Tomohiko Kimura, Seizo Okauchi, Tomoe Kinoshita, Junpei Sanada, Yoshiro Fushimi, Momoyo Nishioka, Akiko Mizoguchi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Published 2019-03-01

Comparison of the effects of three kinds of glucose‐lowering drugs on non‐alcoholic fatty liver disease in patients with type 2 diabetes: A randomized, open‐label, three‐arm, activ...

by Tomoe Kinoshita, Masashi Shimoda, Koji Nakashima, Yoshiro Fushimi, Yurie Hirata, Akihito Tanabe, Fuminori Tatsumi, Hidenori Hirukawa, Junpei Sanada, Kenji Kohara, Shintaro Irie, Tomohiko Kimura, Yoshiko Nakamura, Momoyo Nishioka, Atsushi Obata, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Published 2020-11-01