B-Cell RANKL Contributes to Pathogen-Induced Alveolar Bone Loss in an Experimental Periodontitis Mouse Model

by Rajendra P. Settem, Kiyonobu Honma, Sreedevi Chinthamani, Toshihisa Kawai, Ashu Sharma
Published 2021-09-01

Different engagement of TLR2 and TLR4 in Porphyromonas gingivalis vs. ligature-induced periodontal bone loss

by Mei LIN, Yang HU, Yuhua WANG, Toshihisa KAWAI, Zuomin WANG, Xiaozhe HAN
Published 2017-08-01

Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease

by Mikihito Kajiya, Gabriela Giro, Martin A. Taubman, Xiaozhe Han, Marcia P.A. Mayer, Toshihisa Kawai
Published 2010-11-01

Lipopolysaccharides-Induced Suppression of Innate-Like B Cell Apoptosis Is Enhanced by CpG Oligodeoxynucleotide and Requires Toll-Like Receptors 2 and 4.

by Xiaoqian Yu, Yuhua Wang, Jiang Lin, Yang Hu, Toshihisa Kawai, Martin A Taubman, Xiaozhe Han
Published 2016-01-01

Autoantibodies against muscarinic type 3 receptor in Sjögren's syndrome inhibit aquaporin 5 trafficking.

by Byung Ha Lee, Adrienne E Gauna, Geidys Perez, Yun-jong Park, Kaleb M Pauley, Toshihisa Kawai, Seunghee Cha
Published 2013-01-01

Toll-like receptor agonists Porphyromonas gingivalis LPS and CpG differentially regulate IL-10 competency and frequencies of mouse B10 cells

by Zhiqiang LIU, Yang HU, Pei YU, Mei LIN, Grace HUANG, Toshihisa KAWAI, Martin TAUBMAN, Zuomin WANG, HAN Xiaozhe

Structures and biological activities of novel phosphatidylethanolamine lipids of Porphyromonas gingivalis

by Frank C. Nichols, Birgit Riep, Jiyoung Mun, Martha D. Morton, Toshihisa Kawai, Floyd E. Dewhirst, Michael B. Smith
Published 2006-04-01

GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence.

by Miki Kawada-Matsuo, Yusuke Mazda, Yuichi Oogai, Mikihito Kajiya, Toshihisa Kawai, Sakuo Yamada, Shouichi Miyawaki, Takahiko Oho, Hitoshi Komatsuzawa
Published 2012-01-01

Experimental furcal perforation treated with mineral trioxide aggregate plus selenium: immune response

by Marcela Carvalho ESPALADORI, Kamilla Faria MACIEL, Luciana Carla Neves de BRITO, Toshihisa KAWAI, Leda Quércia VIEIRA, Antônio Paulino RIBEIRO SOBRINHO
Published 2018-10-01

Endodontic medicine: interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials

by Luciano Tavares Angelo Cintra, Carlos Estrela, Mariane Maffei Azuma, Índia Olinta de Azevedo Queiroz, Toshihisa Kawai, João Eduardo Gomes-Filho
Published 2018-10-01

Potential Role of Phosphoglycerol Dihydroceramide Produced by Periodontal Pathogen Porphyromonas gingivalis in the Pathogenesis of Alzheimer’s Disease

by Chiaki Yamada, Juliet Akkaoui, Anny Ho, Carolina Duarte, Richard Deth, Toshihisa Kawai, Frank Nichols, Madepalli K. Lakshmana, Alexandru Movila, Alexandru Movila
Published 2020-11-01

Aggregatibacter actinomycetemcomitans Omp29 is associated with bacterial entry to gingival epithelial cells by F-actin rearrangement.

by Mikihito Kajiya, Hitoshi Komatsuzawa, Annatoula Papantonakis, Makoto Seki, Seicho Makihira, Kazuhisa Ouhara, Yutaka Kusumoto, Shinya Murakami, Martin A Taubman, Toshihisa Kawai
Published 2011-04-01

The involvement of C5a in the progression of experimental arthritis with Porphyromonas gingivalis infection in SKG mice

by Syuichi Munenaga, Kazuhisa Ouhara, Yuta Hamamoto, Mikihito Kajiya, Katsuhiro Takeda, Satoshi Yamasaki, Toshihisa Kawai, Noriyoshi Mizuno, Tsuyoshi Fujita, Eiji Sugiyama, Hidemi Kurihara
Published 2018-11-01

Expression levels of novel cytokine IL-32 in periodontitis and its role in the suppression of IL-8 production by human gingival fibroblasts stimulated with Porphyromonas gingivalis

by Kazuhisa Ouhara, Toshihisa Kawai, Marcelo J.B. Silva, Tsuyoshi Fujita, Kouichi Hayashida, Nadeem Y. Karimbux, Mikihito Kajiya, Hideki Shiba, Hiroyuki Kawaguchi, Hidemi Kurihara
Published 2012-03-01

Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model

by Yuta Hamamoto, Kazuhisa Ouhara, Syuichi Munenaga, Mikio Shoji, Tatsuhiko Ozawa, Jyunzo Hisatsune, Isamu Kado, Mikihito Kajiya, Shinji Matsuda, Toshihisa Kawai, Noriyoshi Mizuno, Tsuyoshi Fujita, Shintaro Hirata, Kotaro Tanimoto, Koji Nakayama, Hiroyuki Kishi, Eiji Sugiyama, Hidemi Kurihara
Published 2020-10-01