Effect of Ocular Hypertension on D-β-Aspartic Acid-Containing Proteins in the Retinas of Rats

by Takashi Kanamoto, Takashi Tachibana, Yasushi Kitaoka, Toshio Hisatomi, Yasuhiro Ikeda, Yusuke Murakami, Kei Tobiume, Ryo Asaoka, Yoshiaki Kiuchi
Published 2019-01-01

TNF-α decreases VEGF secretion in highly polarized RPE cells but increases it in non-polarized RPE cells related to crosstalk between JNK and NF-κB pathways.

by Hiroto Terasaki, Satoru Kase, Makoto Shirasawa, Hiroki Otsuka, Toshio Hisatomi, Shozo Sonoda, Susumu Ishida, Tatsuro Ishibashi, Taiji Sakamoto
Published 2013-01-01

Dynamic increase in extracellular ATP accelerates photoreceptor cell apoptosis via ligation of P2RX7 in subretinal hemorrhage.

by Shoji Notomi, Toshio Hisatomi, Yusuke Murakami, Hiroto Terasaki, Shozo Sonoda, Ryo Asato, Atsunobu Takeda, Yasuhiro Ikeda, Hiroshi Enaida, Taiji Sakamoto, Tatsuro Ishibashi
Published 2013-01-01

Utilizing targeted gene therapy with nanoparticles binding alpha v beta 3 for imaging and treating choroidal neovascularization.

by Hani Salehi-Had, Mi In Roh, Andrea Giani, Toshio Hisatomi, Shintaro Nakao, Ivana K Kim, Evangelos S Gragoudas, Demetrios Vavvas, Samira Guccione, Joan W Miller
Published 2011-04-01

Direct comparison of retinal structure and function in retinitis pigmentosa by co-registering microperimetry and optical coherence tomography.

by Jun Funatsu, Yusuke Murakami, Shunji Nakatake, Masato Akiyama, Kohta Fujiwara, Shotaro Shimokawa, Takashi Tachibana, Toshio Hisatomi, Yoshito Koyanagi, Yukihide Momozawa, Koh-Hei Sonoda, Yasuhiro Ikeda
Published 2019-01-01

The influence of subretinal injection pressure on the microstructure of the monkey retina.

by Kosuke Takahashi, Yuki Morizane, Toshio Hisatomi, Takashi Tachibana, Shuhei Kimura, Mio Morizane Hosokawa, Yusuke Shiode, Masayuki Hirano, Shinichiro Doi, Shinji Toshima, Ryoichi Araki, Hiroshi Matsumae, Yuki Kanzaki, Mika Hosogi, Atsushi Yoshida, Koh-Hei Sonoda, Fumio Shiraga
Published 2018-01-01

Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization

by Takahito Nakama, Shigeo Yoshida, Keijiro Ishikawa, Yuki Kubo, Yoshiyuki Kobayashi, Yedi Zhou, Shintaro Nakao, Toshio Hisatomi, Yasuhiro Ikeda, Kazumasa Takao, Kazunori Yoshikawa, Akira Matsuda, Junya Ono, Shoichiro Ohta, Kenji Izuhara, Akira Kudo, Koh-hei Sonoda, Tatsuro Ishibashi
Published 2017-03-01