Effects of Mild Excitotoxic Stimulus on Mitochondria Ca²⁺ Handling in Hippocampal Cultures of a Mouse Model of Alzheimer’s Disease

by Giulia Rigotto, Lorena Zentilin, Tullio Pozzan, Emy Basso
Published 2021-08-01

Intracellular Calcium Dysregulation by the Alzheimer’s Disease-Linked Protein Presenilin 2

by Luisa Galla, Nelly Redolfi, Tullio Pozzan, Paola Pizzo, Elisa Greotti
Published 2020-01-01

Characterization of the ER-Targeted Low Affinity Ca2+ Probe D4ER

by Elisa Greotti, Andrea Wong, Tullio Pozzan, Diana Pendin, Paola Pizzo
Published 2016-09-01

ORAI2 Down-Regulation Potentiates SOCE and Decreases Aβ42 Accumulation in Human Neuroglioma Cells

by Elena Scremin, Mario Agostini, Alessandro Leparulo, Tullio Pozzan, Elisa Greotti, Cristina Fasolato
Published 2020-07-01

Dampened Slow Oscillation Connectivity Anticipates Amyloid Deposition in the PS2APP Mouse Model of Alzheimer’s Disease

by Alessandro Leparulo, Mufti Mahmud, Elena Scremin, Tullio Pozzan, Stefano Vassanelli, Cristina Fasolato
Published 2019-12-01

Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2

by Riccardo Filadi, Elisa Greotti, Gabriele Turacchio, Alberto Luini, Tullio Pozzan, Paola Pizzo
Published 2016-06-01

Generation and Characterization of a New FRET-Based Ca²⁺ Sensor Targeted to the Nucleus

by Luisa Galla, Nicola Vajente, Diana Pendin, Paola Pizzo, Tullio Pozzan, Elisa Greotti
Published 2021-09-01

The presenilin 2 M239I mutation associated with familial Alzheimer's disease reduces Ca2+ release from intracellular stores

by Giancarlo Zatti, Roberta Ghidoni, Laura Barbiero, Giuliano Binetti, Tullio Pozzan, Cristina Fasolato, Paola Pizzo
Published 2004-03-01

Reduction of Ca2+ stores and capacitative Ca2+ entry is associated with the familial Alzheimer's disease presenilin-2 T122R mutation and anticipates the onset of dementia

by Marta Giacomello, Laura Barbiero, Giancarlo Zatti, Rosanna Squitti, Giuliano Binetti, Tullio Pozzan, Cristina Fasolato, Roberta Ghidoni, Paola Pizzo
Published 2005-04-01

Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer’s Disease

by Alice Rossi, Luisa Galla, Chiara Gomiero, Lorena Zentilin, Mauro Giacca, Valentina Giorgio, Tito Calì, Tullio Pozzan, Elisa Greotti, Paola Pizzo
Published 2021-01-01

New Linear Precursors of cIDPR Derivatives as Stable Analogs of cADPR: A Potent Second Messenger with Ca²⁺-Modulating Activity Isolated from Sea Urchin Eggs

by Stefano D’Errico, Emy Basso, Andrea Patrizia Falanga, Maria Marzano, Tullio Pozzan, Vincenzo Piccialli, Gennaro Piccialli, Giorgia Oliviero, Nicola Borbone
Published 2019-08-01

Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks

by Paola Pizzo, Emy Basso, Riccardo Filadi, Elisa Greotti, Alessandro Leparulo, Diana Pendin, Nelly Redolfi, Michela Rossini, Nicola Vajente, Tullio Pozzan, Cristina Fasolato
Published 2020-09-01

An excitatory loop with astrocytes contributes to drive neurons to seizure threshold.

by Marta Gómez-Gonzalo, Gabriele Losi, Gabriele Losi, Angela Chiavegato, Micaela Zonta, Mario Cammarota, Marco Brondi, Francesco Vetri, Laura Uva, Tullio Pozzan, Marco de Curtis, Gian Michele Ratto, Giorgio Carmignoto
Published 2010-04-01

mCerulean3-Based Cameleon Sensor to Explore Mitochondrial Ca2+ Dynamics In Vivo

by Elisa Greotti, Ilaria Fortunati, Diana Pendin, Camilla Ferrante, Luisa Galla, Lorena Zentilin, Mauro Giacca, Nina Kaludercic, Moises Di Sante, Letizia Mariotti, Annamaria Lia, Marta Gómez-Gonzalo, Michele Sessolo, Giorgio Carmignoto, Renato Bozio, Tullio Pozzan
Published 2019-06-01