p63 and p73 transcriptionally regulate genes involved in DNA repair.

by Yu-Li Lin, Shomit Sengupta, Katherine Gurdziel, George W Bell, Tyler Jacks, Elsa R Flores
Published 2009-10-01

Protocol for single-cell ATAC sequencing using combinatorial indexing in mouse lung adenocarcinoma

by Isabella Del Priore, Sai Ma, Jonathan Strecker, Tyler Jacks, Lindsay M. LaFave, Jason D. Buenrostro
Published 2021-06-01

Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers

by Mandar Deepak Muzumdar, Kimberly Judith Dorans, Katherine Minjee Chung, Rebecca Robbins, Tuomas Tammela, Vasilena Gocheva, Carman Man-Chung Li, Tyler Jacks
Published 2016-09-01

Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma

by Talya L. Dayton, Vasilena Gocheva, Kathryn M. Miller, Arjun Bhutkar, Caroline A. Lewis, Roderick T. Bronson, Matthew G. Vander Heiden, Tyler Jacks
Published 2018-05-01

A Reversible Gene-Targeting Strategy Identifies Synthetic Lethal Interactions between MK2 and p53 in the DNA Damage Response In Vivo

by Sandra Morandell, H. Christian Reinhardt, Ian G. Cannell, Jacob S. Kim, Daniela M. Ruf, Tanya Mitra, Anthony D. Couvillon, Tyler Jacks, Michael B. Yaffe
Published 2013-11-01

Survival of pancreatic cancer cells lacking KRAS function

by Mandar Deepak Muzumdar, Pan-Yu Chen, Kimberly Judith Dorans, Katherine Minjee Chung, Arjun Bhutkar, Erin Hong, Elisa M. Noll, Martin R. Sprick, Andreas Trumpp, Tyler Jacks
Published 2017-10-01

Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma.

by Jeffrey K Mito, Richard F Riedel, Leslie Dodd, Guy Lahat, Alexander J Lazar, Rebecca D Dodd, Lars Stangenberg, William C Eward, Francis J Hornicek, Sam S Yoon, Brian E Brigman, Tyler Jacks, Dina Lev, Sayan Mukherjee, David G Kirsch
Published 2009-11-01

IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development

by Amy Li, Rebecca H. Herbst, David Canner, Jason M. Schenkel, Olivia C. Smith, Jonathan Y. Kim, Michelle Hillman, Arjun Bhutkar, Michael S. Cuoco, C. Garrett Rappazzo, Patricia Rogers, Celeste Dang, Livnat Jerby-Arnon, Orit Rozenblatt-Rosen, Le Cong, Michael Birnbaum, Aviv Regev, Tyler Jacks
Published 2019-12-01

Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

by Alex S. Genshaft, Carly G. K. Ziegler, Constantine N. Tzouanas, Benjamin E. Mead, Alex M. Jaeger, Andrew W. Navia, Ryan P. King, Miyeko D. Mana, Siyi Huang, Vanessa Mitsialis, Scott B. Snapper, Ömer H. Yilmaz, Tyler Jacks, Jeffrey F. Van Humbeck, Alex K. Shalek
Published 2021-09-01

Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

by Alex S Genshaft, Carly G. K. Ziegler, Constantine N. Tzouanas, Benjamin E. Mead, Alex M. Jaeger, Andrew W. Navia, Ryan P. King, Miyeko D. Mana, Siyi Huang, Vanessa Mitsialis, Scott B. Snapper, Ömer H. Yilmaz, Tyler Jacks, Jeffrey F. Van Humbeck, Alex K. Shalek
Published 2021-08-01

Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma

by Allison N Lau, Zhaoqi Li, Laura V Danai, Anna M Westermark, Alicia M Darnell, Raphael Ferreira, Vasilena Gocheva, Sharanya Sivanand, Evan C Lien, Kiera M Sapp, Jared R Mayers, Giulia Biffi, Christopher R Chin, Shawn M Davidson, David A Tuveson, Tyler Jacks, Nicholas J Matheson, Omer Yilmaz, Matthew G Vander Heiden
Published 2020-07-01

Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice

by Bashar Hamza, Alex B. Miller, Lara Meier, Max Stockslager, Sheng Rong Ng, Emily M. King, Lin Lin, Kelsey L. DeGouveia, Nolawit Mulugeta, Nicholas L. Calistri, Haley Strouf, Christina Bray, Felicia Rodriguez, William A. Freed-Pastor, Christopher R. Chin, Grissel C. Jaramillo, Megan L. Burger, Robert A. Weinberg, Alex K. Shalek, Tyler Jacks, Scott R. Manalis
Published 2021-09-01

Investigation of endogenous and adoptively transferred T cell function in a genetic mouse model of lung adenocarcinoma

by Canner, David(David Allen)
Published 2019

Identification of genotype-specific dependencies in Keap1-deficient lung adenocarcinoma

by Romero, Rodrigo,Ph. D.Massachusetts Institute of Technology.
Published 2019

CRISPR-mediated interrogation of small cell lung cancer

by Ng, Sheng Rong
Published 2018

Constructing and deconstructing cancer using CRISPR-Cas9

by Sánchez-Rivera, Francisco J. (Francisco Javier)
Published 2016

Transcriptional regulation of metastatic progression in lung adenocarcinoma

by Li, Carman Man-Chung
Published 2015

MicroRNAs in cellular transformation and tumorigenesis

by Kumar, Madhu S. (Madhu Sudham)
Published 2009

Identifying genes that are required for the maintenance of pancreatic ductal adenocarcinoma

by Jenq, Harry
Published 2013

Functional characterization of the cyclin-dependent kinase inhibitor p21 by gene targeting in the mouse

by Brugarolas, James (James Burfau), 1969-
Published 2009