Neuronal Cell Death Mechanisms in Major Neurodegenerative Diseases

by Hao Chi, Hui-Yun Chang, Tzu-Kang Sang
Published 2018-10-01

Untangling the Tauopathy for Alzheimer’s disease and parkinsonism

by Hui-Yun Chang, Tzu-Kang Sang, Ann-Shyn Chiang
Published 2018-07-01

Cardiac-Restricted Expression of VCP/TER94 RNAi or Disease Alleles Perturbs Drosophila Heart Structure and Impairs Function

by Meera C. Viswanathan, Anna C. Blice-Baum, Tzu-Kang Sang, Anthony Cammarato
Published 2016-05-01

Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model.

by Ya-Chu Chang, Wan-Tzu Hung, Yun-Chin Chang, Henry C Chang, Chia-Lin Wu, Ann-Shyn Chiang, George R Jackson, Tzu-Kang Sang
Published 2011-02-01

VCP maintains nuclear size by regulating the DNA damage-associated MDC1–p53–autophagy axis in Drosophila

by Ya-Chu Chang, Yu-Xiang Peng, Bo-Hua Yu, Henry C. Chang, Pei-Shin Liang, Ting-Yi Huang, Chao-Jie Shih, Li-An Chu, Tzu-Kang Sang
Published 2021-07-01

Derlin-1 regulates mutant VCP-linked pathogenesis and endoplasmic reticulum stress-induced apoptosis.

by Cyong-Jhih Liang, Ya-Chu Chang, Henry C Chang, Chung-Kang Wang, Yu-Chien Hung, Ying-Er Lin, Chia-Ching Chan, Chun-Hong Chen, Hui-Yun Chang, Tzu-Kang Sang
Published 2014-09-01

IBMPFD果蠅模式之建立

by Yun-Ching Chang, 張耘菁