The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation.

by Claudio Scafoglio, Marcus Smolka, Huilin Zhou, Valentina Perissi, Michael G Rosenfeld
Published 2013-01-01

GPS2/KDM4A Pioneering Activity Regulates Promoter-Specific Recruitment of PPARγ

by M. Dafne Cardamone, Bogdan Tanasa, Michelle Chan, Carly T. Cederquist, Jaclyn Andricovich, Michael G. Rosenfeld, Valentina Perissi
Published 2014-07-01

Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue

by Carly T. Cederquist, Claudia Lentucci, Camila Martinez-Calejman, Vanessa Hayashi, Joseph Orofino, David Guertin, Susan K. Fried, Mi-Jeong Lee, M. Dafne Cardamone, Valentina Perissi
Published 2017-01-01

Loss of G-Protein Pathway Suppressor 2 Promotes Tumor Growth Through Activation of AKT Signaling

by Stefanie Chan, Emma Smith, Yuan Gao, Julian Kwan, Benjamin C. Blum, Andrew M. Tilston-Lunel, Isabella Turcinovic, Xaralabos Varelas, Maria Dafne Cardamone, Stefano Monti, Andrew Emili, Andrew Emili, Valentina Perissi
Published 2021-01-01