Quality Considerations When Using Tissue Samples for Biomarker Studies in Cancer Research

by Valerie Speirs
Published 2021-04-01

In vivo models in breast cancer research: progress, challenges and future directions

by Ingunn Holen, Valerie Speirs, Bethny Morrissey, Karen Blyth
Published 2017-04-01

Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses

by Michele Cummings, James Iremonger, Caroline A. Green, Abeer M. Shaaban, Valerie Speirs
Published 2009-01-01

The Sharing Experimental Animal Resources, Coordinating Holdings (SEARCH) Framework: Encouraging Reduction, Replacement, and Refinement in Animal Research.

by Bethny Morrissey, Karen Blyth, Phil Carter, Claude Chelala, Louise Jones, Ingunn Holen, Valerie Speirs
Published 2017-01-01

The SEARCHBreast Portal: A Virtual Bioresource to Facilitate the Sharing of Surplus Animal Materials Derived from Breast Cancer Studies

by Phil Carter, Karen Blyth, Ingunn Holen, Louise Jones, Bethny Morrissey, Valerie Speirs, Claude Chelala
Published 2016-07-01

CIP2A expression predicts recurrences of tamoxifen-treated breast cancer

by Shawn Baldacchino, Laura M Wastall, Christian Saliba, Thomas A Hughes, Christian Scerri, Angelene Berwick, Valerie Speirs, Andrew M Hanby, Godfrey Grech
Published 2017-10-01

Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness

by Alexandra Avgustinova, Marjan Iravani, David Robertson, Antony Fearns, Qiong Gao, Pamela Klingbeil, Andrew M. Hanby, Valerie Speirs, Erik Sahai, Fernando Calvo, Clare M. Isacke
Published 2016-01-01

An Evaluation of Matrix-Containing and Humanised Matrix-Free 3-Dimensional Cell Culture Systems for Studying Breast Cancer.

by Grace C Roberts, Paul G Morris, Marcus A Moss, Sarah L Maltby, Chelsea A Palmer, Claire E Nash, Emily Smart, Deborah L Holliday, Valerie Speirs
Published 2016-01-01

Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer

by Milene Volpato, Michele Cummings, Abeer M. Shaaban, Balkees Abderrahman, Mark A. Hull, Philipp Y. Maximov, Bradley M. Broom, Reiner Hoppe, Ping Fan, Hiltrud Brauch, V. Craig Jordan, Valerie Speirs
Published 2020-10-01

Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis.

by Laura Smith, Euan W Baxter, Philip A Chambers, Caroline A Green, Andrew M Hanby, Thomas A Hughes, Claire E Nash, Rebecca A Millican-Slater, Lucy F Stead, Eldo T Verghese, Valerie Speirs
Published 2015-01-01

Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression

by Anna Di Benedetto, Cristiana Ercolani, Marcella Mottolese, Francesca Sperati, Laura Pizzuti, Patrizia Vici, Irene Terrenato, Abeer M. Shaaban, Matthew P. Humphries, Luigi Di Lauro, Maddalena Barba, Ilio Vitale, Gennaro Ciliberto, Valerie Speirs, Ruggero De Maria, Marcello Maugeri-Saccà
Published 2017-08-01