T-Regulatory Cells in Health and Disease

by Eyad Elkord, Varun Sasidharan Nair
Published 2018-01-01

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications

by Pramod Darvin, Varun Sasidharan Nair, Eyad Elkord
Published 2019-01-01

Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine

by Salman M. Toor, Varun Sasidharan Nair, Eyad Elkord
Published 2020-07-01

Role of circular RNAs in colorectal tumor microenvironment

by Jasni Viralippurath Ashraf, Varun Sasidharan Nair, Reem Saleh, Eyad Elkord
Published 2021-05-01

Immune checkpoint inhibitors: recent progress and potential biomarkers

by Pramod Darvin, Salman M. Toor, Varun Sasidharan Nair, Eyad Elkord
Published 2018-12-01

Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression

by Reem Saleh, Salman M. Toor, Varun Sasidharan Nair, Eyad Elkord, Eyad Elkord
Published 2020-07-01

Integrated Transcriptome and Pathway Analyses Revealed Multiple Activated Pathways in Breast Cancer

by Radhakrishnan Vishnubalaji, Varun Sasidharan Nair, Khalid Ouararhni, Eyad Elkord, Nehad M. Alajez
Published 2019-09-01

Tumor-Infiltrating Lymphoid Cells in Colorectal Cancer Patients with Varying Disease Stages and Microsatellite Instability-High/Stable Tumors

by Salman M. Toor, Varun Sasidharan Nair, Khaled Murshed, Mohamed Abu Nada, Eyad Elkord
Published 2021-01-01

Transcriptomic Analyses of Myeloid-Derived Suppressor Cell Subsets in the Circulation of Colorectal Cancer Patients

by Varun Sasidharan Nair, Reem Saleh, Salman M. Toor, Nehad M. Alajez, Eyad Elkord
Published 2020-09-01

Blockade of PD-1, PD-L1, and TIM-3 Altered Distinct Immune- and Cancer-Related Signaling Pathways in the Transcriptome of Human Breast Cancer Explants

by Reem Saleh, Salman M. Toor, Dana Al-Ali, Varun Sasidharan Nair, Eyad Elkord
Published 2020-06-01

DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients

by Asma A. Elashi, Varun Sasidharan Nair, Rowaida Z. Taha, Hibah Shaath, Eyad Elkord
Published 2019-02-01

PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer

by Reem Saleh, Rowaida Z. Taha, Varun Sasidharan Nair, Nehad M. Alajez, Eyad Elkord
Published 2019-07-01

DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer

by Varun Sasidharan Nair, Salman M. Toor, Rowaida Z. Taha, Hibah Shaath, Eyad Elkord
Published 2018-08-01

DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer

by Varun Sasidharan Nair, Haytham El Salhat, Rowaida Z. Taha, Anne John, Bassam R. Ali, Eyad Elkord
Published 2018-06-01

RNA-Seq Analysis of Colorectal Tumor-Infiltrating Myeloid-Derived Suppressor Cell Subsets Revealed Gene Signatures of Poor Prognosis

by Reem Saleh, Varun Sasidharan Nair, Mahmood Al-Dhaheri, Mahwish Khawar, Mohamed Abu Nada, Nehad M. Alajez, Eyad Elkord, Eyad Elkord
Published 2020-11-01

Differential gene expression of tumor-infiltrating CD4+ T cells in advanced versus early stage colorectal cancer and identification of a gene signature of poor prognosis

by Varun Sasidharan Nair, Reem Saleh, Rowaida Z Taha, Salman M Toor, Khaled Murshed, Ayman A Ahmed, Mohamed A Kurer, Mohamed Abu Nada, Fares Al Ejeh, Eyad Elkord
Published 2020-01-01

Differential gene expression of tumor-infiltrating CD8+ T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis

by Reem Saleh, Varun Sasidharan Nair, Salman M Toor, Rowaida Z Taha, Khaled Murshed, Mahmood Al-Dhaheri, Mahwish Khawar, Mahir Abdulla Petkar, Mohamed Abu Nada, Fares Al-Ejeh, Eyad Elkord
Published 2020-07-01

Transcriptome of Tumor-Infiltrating T Cells in Colorectal Cancer Patients Uncovered a Unique Gene Signature in CD4⁺ T Cells Associated with Poor Disease-Specific Surviva...

by Salman M. Toor, Varun Sasidharan Nair, Reem Saleh, Rowaida Z. Taha, Khaled Murshed, Mahmood Al-Dhaheri, Mahwish Khawar, Ayman A. Ahmed, Mohamed A. Kurer, Mohamed Abu Nada, Eyad Elkord
Published 2021-04-01

Transcriptomic Profiling of Tumor-Infiltrating CD4⁺TIM-3⁺ T Cells Reveals Their Suppressive, Exhausted, and Metastatic Characteristics in Colorectal Cancer Pa...

by Varun Sasidharan Nair, Salman M Toor, Rowaida Z Taha, Ayman A Ahmed, Mohamed A Kurer, Khaled Murshed, Madiha E Soofi, Khalid Ouararhni, Nehad M. Alajez, Mohamed Abu Nada, Eyad Elkord
Published 2020-02-01