Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1.

by Ravi Chopra, David D Bushart, Vikram G Shakkottai
Published 2018-01-01

FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons

by Vikram G. Shakkottai, Maolei Xiao, Lin Xu, Michael Wong, Jeanne M. Nerbonne, David M. Ornitz, Kelvin A. Yamada
Published 2009-01-01

Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcayji-hes mice

by Katiuska Luna-Cancalon, Kristine M. Sikora, Samuel S. Pappas, Vikrant Singh, Heike Wulff, Henry L. Paulson, Margit Burmeister, Vikram G. Shakkottai
Published 2014-07-01

Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD

by Mark L. Schultz, Kelsey L. Krus, Susmita Kaushik, Derek Dang, Ravi Chopra, Ling Qi, Vikram G. Shakkottai, Ana Maria Cuervo, Andrew P. Lieberman
Published 2018-09-01

Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease.

by Chan Chung, Matthew J Elrick, James M Dell'Orco, Zhaohui S Qin, Shanker Kalyana-Sundaram, Arul M Chinnaiyan, Vikram G Shakkottai, Andrew P Lieberman
Published 2016-05-01

Antisense oligonucleotide therapy rescues aggresome formation in a novel spinocerebellar ataxia type 3 human embryonic stem cell line

by Lauren R. Moore, Laura Keller, David D. Bushart, Rodrigo G. Delatorre, Duojia Li, Hayley S. McLoughlin, Maria do Carmo Costa, Vikram G. Shakkottai, Gary D. Smith, Henry L. Paulson
Published 2019-08-01

Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder

by Julie M. Jones, Louise Dionne, James Dell'Orco, Rachel Parent, Jamie N. Krueger, Xiaoyang Cheng, Sulayman D. Dib-Hajj, Rosie K. Bunton-Stasyshyn, Lisa M. Sharkey, James J. Dowling, Geoffrey G. Murphy, Vikram G. Shakkottai, Peter Shrager, Miriam H. Meisler
Published 2016-05-01

Vascular Risk Factors and Clinical Progression in Spinocerebellar Ataxias

by Raymond Y. Lo, Karla P. Figueroa, Stefan M. Pulst, Chi-Ying Lin, Susan Perlman, George Wilmot, Christopher M. Gomez, Jeremy Schmahmann, Henry Paulson, Vikram G. Shakkottai, Sarah H. Ying, Theresa Zesiewicz, Khalaf Bushara, Michael Geschwind, Guangbin Xia, S S. Subramony, Tetsuo Ashizawa, Sheng-Han Kuo
Published 2015-02-01

Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases

by Mark L. Schultz, Maria V. Fawaz, Ruth D. Azaria, Todd C. Hollon, Elaine A. Liu, Thaddeus J. Kunkel, Troy A. Halseth, Kelsey L. Krus, Ran Ming, Emily E. Morin, Hayley S. McLoughlin, David D. Bushart, Henry L. Paulson, Vikram G. Shakkottai, Daniel A. Orringer, Anna S. Schwendeman, Andrew P. Lieberman
Published 2019-11-01