Bone marrow stromal cells induce an ALDH+ stem cell-like phenotype and enhance therapy resistance in AML through a TGF-β-p38-ALDH2 pathway.

by Bin Yuan, Fouad El Dana, Stanley Ly, Yuanqing Yan, Vivian Ruvolo, Elizabeth J Shpall, Marina Konopleva, Michael Andreeff, Venkata Lokesh Battula
Published 2020-01-01

MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation.

by Gautam Borthakur, Seshagiri Duvvuri, Vivian Ruvolo, Durga Nand Tripathi, Sujan Piya, Jared Burks, Rodrigo Jacamo, Kensuke Kojima, Peter Ruvolo, Juan Fueyo-Margareto, Marina Konopleva, Michael Andreeff
Published 2015-01-01

Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs.

by Jo Ishizawa, Kensuke Kojima, Teresa McQueen, Vivian Ruvolo, Dhruv Chachad, Graciela M Nogueras-Gonzalez, Xuelin Huang, William E Pierceall, E J Dettman, Michael H Cardone, Sharon Shacham, Marina Konopleva, Michael Andreeff
Published 2015-01-01