Nitric Oxide and S-Nitrosylation in Cardiac Regulation: G Protein-Coupled Receptor Kinase-2 and β-Arrestins as Targets

by Gizem Kayki-Mutlu, Walter J. Koch
Published 2021-01-01

New Insights in Cardiac β-Adrenergic Signaling During Heart Failure and Aging

by Claudio de Lucia, Akito Eguchi, Walter J. Koch
Published 2018-08-01

Targeting cardiac beta-adrenergic signaling via GRK2 inhibition for heart failure therapy

by Alessandro eCannavo, Daniela eLiccardo, Walter J. Koch
Published 2013-09-01

In Vivo Stimulation of α- and β-Adrenoceptors in Mice Differentially Alters Small RNA Content of Circulating Extracellular Vesicles

by Jin-Sook Kwon, Eric W. Barr, J. Kurt Chuprun, Walter J. Koch
Published 2021-05-01

Targeting GRK5 for Treating Chronic Degenerative Diseases

by Federica Marzano, Antonio Rapacciuolo, Nicola Ferrara, Giuseppe Rengo, Walter J. Koch, Alessandro Cannavo
Published 2021-02-01

Identification and Characterization of Amlexanox as a G Protein-Coupled Receptor Kinase 5 Inhibitor

by Kristoff T. Homan, Emily Wu, Alessandro Cannavo, Walter J. Koch, John J. G. Tesmer
Published 2014-10-01

Identification and Comparison of Hyperglycemia-Induced Extracellular Vesicle Transcriptome in Different Mouse Stem Cells

by Grace Huang, Venkata Naga Srikanth Garikipati, Yan Zhou, Cynthia Benedict, Steven R. Houser, Walter J. Koch, Raj Kishore
Published 2020-09-01

Ethyl Pyruvate Modulates Murine Dendritic Cell Activation and Survival Through Their Immunometabolism

by Marita Chakhtoura, Robert W. Chain, Priscila Y. Sato, Priscila Y. Sato, Connie C. Qiu, Michael H. Lee, Joseph J. Meissler, Joseph J. Meissler, Toby K. Eisenstein, Toby K. Eisenstein, Walter J. Koch, Walter J. Koch, Roberto Caricchio, Stefania Gallucci
Published 2019-01-01

Cigarette Smoke and Inflammation: Role in Cerebral Aneurysm Formation and Rupture

by Nohra Chalouhi, Muhammad S. Ali, Robert M. Starke, Pascal M. Jabbour, Stavropoula I. Tjoumakaris, L. Fernando Gonzalez, Robert H. Rosenwasser, Walter J. Koch, Aaron S. Dumont
Published 2012-01-01

Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases

by Alessandro Cannavo, Daniela Liccardo, Akito Eguchi, Katherine J. Elliott, Christopher J. Traynham, Jessica Ibetti, Satoru Eguchi, Dario Leosco, Nicola Ferrara, Giuseppe Rengo, Walter J. Koch
Published 2016-03-01

Tumor necrosis factor-α and lymphotoxin-α mediate myocardial ischemic injury via TNF receptor 1, but are cardioprotective when activating TNF receptor 2.

by Yanqing Zhang, Jianli Zhao, Wayne Bond Lau, Li-Yuan Jiao, Baojiang Liu, Yuexing Yuan, Xiaoliang Wang, Erhe Gao, Walter J Koch, Xin-Liang Ma, Yajing Wang
Published 2013-01-01

Cigarette smoke modulates vascular smooth muscle phenotype: implications for carotid and cerebrovascular disease.

by Robert M Starke, Muhammad S Ali, Pascal M Jabbour, Stavropoula I Tjoumakaris, Fernando Gonzalez, David M Hasan, Robert H Rosenwasser, Gary K Owens, Walter J Koch, Aaron S Dumont
Published 2013-01-01

Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process.

by Jessica I Gold, Jeffrey S Martini, Jonathan Hullmann, Erhe Gao, J Kurt Chuprun, Linda Lee, Douglas G Tilley, Joseph E Rabinowitz, Julie Bossuyt, Donald M Bers, Walter J Koch
Published 2013-01-01

Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway.

by Qian Fan, Mai Chen, Lin Zuo, Xiying Shang, Maggie Z Huang, Michele Ciccarelli, Philip Raake, Henriette Brinks, Kurt J Chuprun, Gerald W Dorn, Walter J Koch, Erhe Gao
Published 2013-01-01

G protein-coupled receptor kinase 2 promotes cardiac hypertrophy.

by Philipp Schlegel, Julia Reinkober, Eric Meinhardt, Henrike Tscheschner, Erhe Gao, Sarah M Schumacher, Ancai Yuan, Johannes Backs, Patrick Most, Thomas Wieland, Walter J Koch, Hugo A Katus, Philip W Raake
Published 2017-01-01

LIN28a induced metabolic and redox regulation promotes cardiac cell survival in the heart after ischemic injury

by Antonia Elizabeth Yuko, Vagner Oliveira Carvalho Rigaud, Justin Kurian, Ji H. Lee, Nicole Kasatkin, Michael Behanan, Tao Wang, Anna Maria Luchesse, Sadia Mohsin, Walter J. Koch, Hong Wang, Mohsin Khan
Published 2021-11-01

The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition

by Timothy S. Luongo, Jonathan P. Lambert, Ancai Yuan, Xueqian Zhang, Polina Gross, Jianliang Song, Santhanam Shanmughapriya, Erhe Gao, Mohit Jain, Steven R. Houser, Walter J. Koch, Joseph Y. Cheung, Muniswamy Madesh, John W. Elrod
Published 2015-07-01

Aldosterone Jeopardizes Myocardial Insulin and β-Adrenergic Receptor Signaling via G Protein-Coupled Receptor Kinase 2

by Alessandro Cannavo, Alessandro Cannavo, Federica Marzano, Andrea Elia, Daniela Liccardo, Leonardo Bencivenga, Giuseppina Gambino, Claudia Perna, Antonio Rapacciuolo, Antonio Cittadini, Nicola Ferrara, Nicola Ferrara, Nazareno Paolocci, Nazareno Paolocci, Walter J. Koch, Giuseppe Rengo, Giuseppe Rengo
Published 2019-08-01

microRNA in Cardiovascular Aging and Age-Related Cardiovascular Diseases

by Claudio de Lucia, Claudio de Lucia, Klara Komici, Giulia Borghetti, Grazia Daniela Femminella, Leonardo Bencivenga, Alessandro Cannavo, Alessandro Cannavo, Graziamaria Corbi, Nicola Ferrara, Nicola Ferrara, Steven R. Houser, Walter J. Koch, Giuseppe Rengo, Giuseppe Rengo
Published 2017-06-01

Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System

by Alessandro Cannavo, Alessandro Cannavo, Daniela Liccardo, Daniela Liccardo, Klara Komici, Graziamaria Corbi, Claudio de Lucia, Grazia D. Femminella, Andrea Elia, Leonardo Bencivenga, Nicola Ferrara, Nicola Ferrara, Walter J. Koch, Nazareno Paolocci, Nazareno Paolocci, Giuseppe Rengo, Giuseppe Rengo
Published 2017-08-01