Sterols, Oxysterols, and Accessible Cholesterol: Signalling for Homeostasis, in Immunity and During Development

by William J. Griffiths, Yuqin Wang
Published 2021-10-01

Are 15-oxygenated sterols present in the human circulation?1

by William J. Griffiths, Yuqin Wang
Published 2011-01-01

Bile acids: analysis in biological fluids and tissues

by William J. Griffiths, Jan Sjövall
Published 2010-01-01

Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C1

by Gunvor Alvelius, Ola Hjalmarson, William J. Griffiths, Ingemar Björkhem, Jan Sjövall
Published 2001-10-01

Developing an Enzyme-Assisted Derivatization Method for Analysis of C₂₇ Bile Alcohols and Acids by Electrospray Ionization-Mass Spectrometry

by Jonas Abdel-Khalik, Peter J. Crick, Eylan Yutuc, Yuqin Wang, William J. Griffiths
Published 2019-02-01

The Biosynthesis of Enzymatically Oxidized Lipids

by Ali A. Hajeyah, William J. Griffiths, Yuqin Wang, Andrew J. Finch, Valerie B. O’Donnell
Published 2020-11-01

Shorthand notation for lipid structures derived from mass spectrometry

by Gerhard Liebisch, Juan Antonio Vizcaíno, Harald Köfeler, Martin Trötzmüller, William J. Griffiths, Gerd Schmitz, Friedrich Spener, Michael J.O. Wakelam
Published 2013-06-01

Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterolss⃞

by Kersti Karu, Martin Hornshaw, Gary Woffendin, Karl Bodin, Mats Hamberg, Gunvor Alvelius, Jan Sjövall, John Turton, Yuqin Wang, William J. Griffiths
Published 2007-04-01

Mining for Oxysterols in <i>Cyp7b1^−/−</i> Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5

by Anna Meljon, Peter J. Crick, Eylan Yutuc, Joyce L. Yau, Jonathan R. Seckl, Spyridon Theofilopoulos, Ernest Arenas, Yuqin Wang, William J. Griffiths
Published 2019-04-01

Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle

by Nicholas J. Hudson, Antonio Reverter, William J. Griffiths, Eylan Yutuc, Yuqin Wang, Angela Jeanes, Sean McWilliam, David W. Pethick, Paul L. Greenwood
Published 2020-01-01

Analysis of bioactive oxysterols in newborn mouse brain by LC/MS

by Anna Meljon, Spyridon Theofilopoulos, Cedric H.L. Shackleton, Gordon L. Watson, Norman B. Javitt, Hans-Joachim Knölker, Ratni Saini, Ernest Arenas, Yuqin Wang, William J. Griffiths
Published 2012-11-01

Defective cholesterol metabolism in amyotrophic lateral sclerosis

by Jonas Abdel-Khalik, Eylan Yutuc, Peter J. Crick, Jan-Åke Gustafsson, Margaret Warner, Gustavo Roman, Kevin Talbot, Elizabeth Gray, William J. Griffiths, Martin R. Turner, Yuqin Wang
Published 2017-01-01

On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO

by Ingemar Björkhem, Ulf Diczfalusy, Anita Lövgren-Sandblom, Lena Starck, Monica Jonsson, Keri Tallman, Henrik Schirmer, Lilian Bomme Ousager, Peter J. Crick, Yuqin Wang, William J. Griffiths, F. Peter Guengerich
Published 2014-06-01

Identification of unusual oxysterols and bile acids with 7-oxo or 3β,5α,6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage fragmentation[S]...

by William J. Griffiths, Ian Gilmore, Eylan Yutuc, Jonas Abdel-Khalik, Peter J. Crick, Thomas Hearn, Alison Dickson, Brian W. Bigger, Teresa Hoi-Yee Wu, Anu Goenka, Arunabha Ghosh, Simon A. Jones, Yuqin Wang
Published 2018-01-01

Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis

by Philip Höflinger, Stefan Hauser, Eylan Yutuc, Holger Hengel, Lauren Griffiths, Florentine Radelfahr, Owain W. Howell, Yuqin Wang, Sonja L. Connor, P. Barton Duell, Andrea E. DeBarber, Peter Martus, Dieter Lütjohann, William J. Griffiths, Ludger Schöls
Published 2021-01-01

Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures

by Gerhard Liebisch, Eoin Fahy, Junken Aoki, Edward A. Dennis, Thierry Durand, Christer S. Ejsing, Maria Fedorova, Ivo Feussner, William J. Griffiths, Harald Köfeler, Alfred H. Merrill, Jr., Robert C. Murphy, Valerie B. O'Donnell, Olga Oskolkova, Shankar Subramaniam, Michael J.O. Wakelam, Friedrich Spener
Published 2020-12-01

The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson’s Disease and Their Association With Disease State and Clinical Features

by William J. Griffiths, Jonas Abdel-Khalik, Sarah F. Moore, Ruwani S. Wijeyekoon, Peter J. Crick, Eylan Yutuc, Krista Farrell, David P. Breen, David P. Breen, David P. Breen, Caroline H. Williams-Gray, Spyridon Theofilopoulos, Ernest Arenas, Miles Trupp, Roger A. Barker, Roger A. Barker, Yuqin Wang
Published 2021-08-01

Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis[S]

by Tina Raselli, Tom Hearn, Annika Wyss, Kirstin Atrott, Alain Peter, Isabelle Frey-Wagner, Marianne R. Spalinger, Ewerton M. Maggio, Andreas W. Sailer, Johannes Schmitt, Philipp Schreiner, Anja Moncsek, Joachim Mertens, Michael Scharl, William J. Griffiths, Marco Bueter, Andreas Geier, Gerhard Rogler, Yuqin Wang, Benjamin Misselwitz
Published 2019-07-01

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway.

by Kevin A Robertson, Wei Yuan Hsieh, Thorsten Forster, Mathieu Blanc, Hongjin Lu, Peter J Crick, Eylan Yutuc, Steven Watterson, Kimberly Martin, Samantha J Griffiths, Anton J Enright, Mami Yamamoto, Madapura M Pradeepa, Kimberly A Lennox, Mark A Behlke, Simon Talbot, Jürgen Haas, Lars Dölken, William J Griffiths, Yuqin Wang, Ana Angulo, Peter Ghazal
Published 2016-03-01

Quality control requirements for the correct annotation of lipidomics data

by Harald C. Köfeler, Thomas O. Eichmann, Robert Ahrends, John A. Bowden, Niklas Danne-Rasche, Edward A. Dennis, Maria Fedorova, William J. Griffiths, Xianlin Han, Jürgen Hartler, Michal Holčapek, Robert Jirásko, Jeremy P. Koelmel, Christer S. Ejsing, Gerhard Liebisch, Zhixu Ni, Valerie B. O’Donnell, Oswald Quehenberger, Dominik Schwudke, Andrej Shevchenko, Michael J. O. Wakelam, Markus R. Wenk, Denise Wolrab, Kim Ekroos
Published 2021-08-01