Intestinal epithelial plasticity and regeneration via cell dedifferentiation

by Yuan Liu, Ye-Guang Chen
Published 2020-09-01

Welcome to Cell Regeneration

by Ye-Guang Chen, Ying Lou
Published 2020-06-01

Regulation of TGF-β Signal Transduction

by Bing Zhao, Ye-Guang Chen
Published 2014-01-01

2D- and 3D-Based Intestinal Stem Cell Cultures for Personalized Medicine

by Yuan Liu, Ye-Guang Chen
Published 2018-11-01

Generation of 3D human gastrointestinal organoids: principle and applications

by Mengxian Zhang, Yuan Liu, Ye-Guang Chen
Published 2020-06-01

Dedifferentiation: the return road to repair the intestinal epithelium

by Yuan Liu, Xiaochen Xiong, Ye-Guang Chen
Published 2020-06-01

Establishment of porcine and monkey colonic organoids for drug toxicity study

by Haonan Li, Yalong Wang, Mengxian Zhang, Hong Wang, Along Cui, Jianguo Zhao, Weizhi Ji, Ye-Guang Chen
Published 2021-10-01

Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death.

by Pan Ye, Y Jeffrey Chiang, Zhen Qi, Yehua Li, Shan Wang, Yuan Liu, Xintong Li, Ye-Guang Chen
Published 2018-09-01

Four amino acids within a tandem QxVx repeat in a predicted extended α-helix of the Smad-binding domain of Sip1 are necessary for binding to activated Smad proteins.

by Andrea Conidi, Veronique van den Berghe, Kris Leslie, Agata Stryjewska, Hua Xue, Ye-Guang Chen, Eve Seuntjens, Danny Huylebroeck
Published 2013-01-01

DNA Damage Activates TGF-β Signaling via ATM-c-Cbl-Mediated Stabilization of the Type II Receptor TβRII

by Yuzhen Li, Yuan Liu, Y. Jeffrey Chiang, Fei Huang, Yehua Li, Xintong Li, Yuanheng Ning, Wenhao Zhang, Haiteng Deng, Ye-Guang Chen
Published 2019-07-01

Noncanonical TGF-β signaling leads to FBXO3-mediated degradation of ΔNp63α promoting breast cancer metastasis and poor clinical prognosis.

by Mengmeng Niu, Yajun He, Jing Xu, Liangping Ding, Tao He, Yong Yi, Mengyuan Fu, Rongtian Guo, Fengtian Li, Hu Chen, Ye-Guang Chen, Zhi-Xiong Jim Xiao
Published 2021-02-01

BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes

by Zhen Qi, Yehua Li, Bing Zhao, Chi Xu, Yuan Liu, Haonan Li, Bingjie Zhang, Xinquan Wang, Xiao Yang, Wei Xie, Baojie Li, Jing-Dong Jackie Han, Ye-Guang Chen
Published 2017-01-01

Identification of the proliferation/differentiation switch in the cellular network of multicellular organisms.

by Kai Xia, Huiling Xue, Dong Dong, Shanshan Zhu, Jiamu Wang, Qingpeng Zhang, Lei Hou, Hua Chen, Ran Tao, Zheng Huang, Zheng Fu, Ye-Guang Chen, Jing-Dong J Han
Published 2006-11-01

Positive feedback of SuFu negating protein 1 on Hedgehog signaling promotes colorectal tumor growth

by Zhengwei Yan, Minzhang Cheng, Guohui Hu, Yao Wang, Shaopeng Zeng, Aidi Huang, Linlin Xu, Yuan Liu, Chao Shi, Libin Deng, Quqin Lu, Hai Rao, Hua Lu, Ye-Guang Chen, Shiwen Luo
Published 2021-02-01

Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway

by Dan He, Hongguang Wu, Jinnan Xiang, Xinsen Ruan, Peike Peng, Yuanyuan Ruan, Ye-Guang Chen, Yibin Wang, Qiang Yu, Hongbing Zhang, Samy L. Habib, Ronald A. De Pinho, Huijuan Liu, Baojie Li
Published 2020-01-01