Tislelizumab uniquely binds to the CC′ loop of PD‐1 with slow‐dissociated rate and complete PD‐L1 blockage

by Yuan Hong, Yingcai Feng, Hanzi Sun, Bo Zhang, Hongfu Wu, Qing Zhu, Yucheng Li, Tong Zhang, Yilu Zhang, Xinxin Cui, Zhuo Li, Xiaomin Song, Kang Li, Mike Liu, Ye Liu
Published 2021-03-01

699 A differentiated anti-OX40 agonist BGB-A445 does not block OX40-OX40L interaction and reveals remarkable anti-tumor efficacy in preclinical models

by Bo Zhang, Ye Liu, Kang Li, Yuan Hong, Tong Zhang, Beibei Jiang, Zuobai Wang, Yingcai Feng, Haiying Li, Wenfeng Gong, Xing Wang, Yajuan Gao, Xiaosui Zhou, Zilin Wang, Hongjia Hou, Hanzi Sun, Xiaomin Song, Xuesong Liu
Published 2020-11-01