Site-specific PEGylation of lidamycin and its antitumor activity

by Liang Li, Boyang Shang, Lei Hu, Rongguang Shao, Yongsu Zhen
Published 2015-05-01

A novel enediyne‐integrated antibody–drug conjugate shows promising antitumor efficacy against CD30+ lymphomas

by Rong Wang, Liang Li, Shenghua Zhang, Yi Li, Xiaofei Wang, Qingfang Miao, Yongsu Zhen
Published 2018-03-01

An Engineered Fusion Protein Anti-CD19(Fab)-LDM Effectively Inhibits ADR-Resistant B Cell Lymphoma

by Dongmei Fan, Linlin Jiang, Yuewen Song, Shiqi Bao, Yuanyuan Yang, Xiangfei Yuan, Yongsu Zhen, Ming Yang, Dongsheng Xiong
Published 2019-09-01

A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway.

by Jianhua Gong, Yanbo Zheng, Ying Wang, Weijin Sheng, Yi Li, Xiujun Liu, Shuyi Si, Rongguang Shao, Yongsu Zhen
Published 2018-01-01