Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.

by Baichun Jiang, Wei Zhao, Jupeng Yuan, Yanyan Qian, Wenjie Sun, Yongxin Zou, Chenhong Guo, Bingxi Chen, Changshun Shao, Yaoqin Gong
Published 2012-01-01

Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks.

by Bing Xu, Zhaoliang Sun, Zhaojian Liu, Haiyang Guo, Qiao Liu, Haiyan Jiang, Yongxin Zou, Yaoqin Gong, Jay A Tischfield, Changshun Shao
Published 2011-04-01

Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells

by Boxuan Li, Dong Hou, Haiyang Guo, Haibin Zhou, Shouji Zhang, Xiuhua Xu, Qiao Liu, Xiyu Zhang, Yongxin Zou, Yaoqin Gong, Changshun Shao
Published 2017-03-01

CUL4B Promotes Temozolomide Resistance in Gliomas by Epigenetically Repressing CDNK1A Transcription

by Xiang Ye, Xiang Ye, Xiaochen Liu, Min Gao, Li Gong, Fei Tian, Yangli Shen, Huili Hu, Gongping Sun, Yongxin Zou, Yaoqin Gong
Published 2021-04-01

KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1

by Lei Liu, Jianfeng Cui, Yajing Zhao, Xiaochen Liu, Lipeng Chen, Yangyang Xia, Yong Wang, Shouzhen Chen, Shuna Sun, Benkang Shi, Yongxin Zou
Published 2021-05-01

Wogonin Induces Apoptosis and Reverses Sunitinib Resistance of Renal Cell Carcinoma Cells via Inhibiting CDK4-RB Pathway

by Yong Wang, Yong Wang, Yong Wang, Shouzhen Chen, Shouzhen Chen, Shuna Sun, Guangyi Liu, Lipeng Chen, Lipeng Chen, Yangyang Xia, Yangyang Xia, Jianfeng Cui, Jianfeng Cui, Wenfu Wang, Wenfu Wang, Xuewen Jiang, Xuewen Jiang, Lei Zhang, Yaofeng Zhu, Yongxin Zou, Benkang Shi, Benkang Shi
Published 2020-07-01