Antiarrhythmic Properties of a Prior Oral Loading of Amiodarone in In Vivo Canine Coronary Ligation/Reperfusion-Induced Arrhythmia Model: Comparison With Other Class III Antiarrhyt...

by Yoshinobu Nagasawa, Jianguang Chen, Keitaro Hashimoto
Published 2005-01-01

Topics on the Na+/Ca2+ Exchanger: Involvement of Na+/Ca2+ Exchange System in Cardiac Triggered Activity

by Nobuo Homma, Md Shah Amran, Yoshinobu Nagasawa, Keitaro Hashimoto
Published 2006-01-01

In vivo analysis of torsadogenic potential of an antipsychotic drug paliperidone using the acute atrioventricular block rabbit as a proarrhythmia model

by Mihoko Hagiwara, Ryuichi Kambayashi, Megumi Aimoto, Yoshinobu Nagasawa, Akira Takahara
Published 2016-09-01

Relationship Between Phosphodiesterase Inhibition Induced by Several Kampo Medicines and Smooth Muscle Relaxation of Gastrointestinal Tract Tissues of Rats

by Yoshiki Saegusa, Atsushi Sugiyama, Akira Takahara, Yoshinobu Nagasawa, Keitaro Hashimoto
Published 2003-01-01

Effect of the Sarcolemmal KATP Channel Blocker HMR1098 on Arrhythmias Induced by Programmed Electrical Stimulation in Canine Old Myocardial Infarction Model: Comparison With Gliben...

by Bing-Mei Zhu, Shigeki Miyamoto, Yoshinobu Nagasawa, Teruaki Wajima, Keitaro Hashimoto
Published 2003-01-01

Electropharmacological profile of an atrial-selective sodium channel blocker acehytisine assessed in the isoflurane-anesthetized guinea-pig model

by Xin Cao, Yoshinobu Nagasawa, Chengshun Zhang, Hanxiao Zhang, Megumi Aimoto, Akira Takahara
Published 2019-12-01

Sensitivity of inhalation anesthetics isoflurane and sevoflurane for the drug-induced QT-interval prolongation in guinea pigs

by Yoshinobu Nagasawa, Kaori Sakai, Rui Kurimoto, Satoshi Kawakami, Megumi Aimoto, Akira Takahara
Published 2020-05-01

Acehytisine suppresses atrial fibrillation in rats with dilated atria caused by chronic volume overload

by Xin Cao, Yoshinobu Nagasawa, Chengshun Zhang, Hanxiao Zhang, Megumi Aimoto, Akira Takahara
Published 2020-01-01

Pravastatin Inhibits Arrhythmias Induced by Coronary Artery Ischemia in Anesthetized Rats

by Jianguang Chen, Hua Shen, Yoshinobu Nagasawa, Kazuhiro Mitsui, Kunio Tsurugi, Keitaro Hashimoto
Published 2007-01-01

Influence of chronic volume overload-induced atrial remodeling on electrophysiological responses to cholinergic receptor stimulation in the isolated rat atria

by Xin Cao, Megumi Aimoto, Marie Fukumoto, Yoshinobu Nagasawa, Hikaru Tanaka, Akira Takahara
Published 2018-02-01

Torsadogenic potential of a novel remyelinating drug clemastine for multiple sclerosis assessed in the rabbit proarrhythmia model

by Satoshi Kawakami, Yoshinobu Nagasawa, Mihoko Hagiwara-Nagasawa, Kensuke Omura, Megumi Aimoto, Akira Takahara
Published 2020-11-01

Selectivity of Ca2+ channel blockers for dilator actions on the isolated lower esophageal sphincter and aorta from rats

by Akira Takahara, Shuhei Nozaki, Akane Ishiguro, Kaori Okamura, Xin Cao, Megumi Aimoto, Yoshinobu Nagasawa
Published 2018-05-01

Pravastatin Prevents Arrhythmias Induced by Coronary Artery Ischemia/Reperfusion in Anesthetized Normocholesterolemic Rats

by Jianguang Chen, Yoshinobu Nagasawa, Bing-Mei Zhu, Masami Ohmori, Ken-ichi Harada, Akio Fujimura, Keitaro Hashimoto
Published 2003-01-01

Angiotensin II acutely increases arterial stiffness as monitored by cardio-ankle vascular index (CAVI) in anesthetized rabbits

by Kiyoshi Sakuma, Akira Shimoda, Hiroaki Shiratori, Tetsuya Komatsu, Kento Watanabe, Tatsuo Chiba, Megumi Aimoto, Yoshinobu Nagasawa, Yuichi Hori, Kohji Shirai, Akira Takahara
Published 2019-06-01

Physiological role of nitric oxide for regulation of arterial stiffness in anesthetized rabbits

by Tatsuo Chiba, Kiyoshi Sakuma, Tetsuya Komatsu, Xin Cao, Megumi Aimoto, Yoshinobu Nagasawa, Kazuhiro Shimizu, Mao Takahashi, Yuichi Hori, Kohji Shirai, Akira Takahara
Published 2019-01-01