Non-Coding Micro RNAs and Hypoxia-Inducible Factors Are Selenium Targets for Development of a Mechanism-Based Combination Strategy in Clear-Cell Renal Cell Carcinoma—Bench-to-Bedsi...

by Youcef M. Rustum, Sreenivasulu Chintala, Farukh A. Durrani, Arup Bhattacharya
Published 2018-10-01

A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity.

by Xiang Ling, Shousong Cao, Qiuying Cheng, James T Keefe, Youcef M Rustum, Fengzhi Li
Published 2012-01-01

Activity of the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid against Human Head and Neck Carcinoma Xenografts

by Mukund Seshadri, Richard Mazurchuk, Joseph A. Spernyak, Arup Bhattacharya, Youcef M. Rustum, David A. Bellnier
Published 2006-07-01

Hypoxia-Specific Drug Tirapazamine Does Not Abrogate Hypoxic Tumor Cells in Combination Therapy with Irinotecan and Methylselenocysteine in Well-Differentiated Human Head and Neck...

by Arup Bhattacharya, Károly Tóth, Farukh A. Durrani, Shousong Cao, Harry K. Slocum, Sreenivasulu Chintala, Youcef M. Rustum
Published 2008-08-01

Architectural Heterogeneity in Tumors Caused by Differentiation Alters Intratumoral Drug Distribution and Affects Therapeutic Synergy of Antiangiogenic Organoselenium Compound

by Youcef M. Rustum, Károly Tóth, Mukund Seshadri, Arindam Sen, Farukh A. Durrani, Emily Stott, Carl D. Morrison, Shousong Cao, Arup Bhattacharya
Published 2010-01-01