Intercellular Communication by Vascular Endothelial Cell-Derived Extracellular Vesicles and Their MicroRNAs in Respiratory Diseases

by Shota Fujimoto, Yu Fujita, Yu Fujita, Tsukasa Kadota, Jun Araya, Kazuyoshi Kuwano
Published 2021-01-01

Development of Small RNA Delivery Systems for Lung Cancer Therapy

by Yu Fujita, Kazuyoshi Kuwano, Takahiro Ochiya
Published 2015-03-01

RNAi Therapeutic Platforms for Lung Diseases

by Kazuyoshi Kuwano, Takahiro Ochiya, Fumitaka Takeshita, Yu Fujita
Published 2013-02-01

The Impact of Extracellular Vesicle-Encapsulated Circulating MicroRNAs in Lung Cancer Research

by Yu Fujita, Kazuyoshi Kuwano, Takahiro Ochiya, Fumitaka Takeshita
Published 2014-01-01

Role of chaperone-mediated autophagy in the pathophysiology including pulmonary disorders

by Yusuke Hosaka, Jun Araya, Yu Fujita, Kazuyoshi Kuwano
Published 2021-10-01

Clinical Application of Mesenchymal Stem Cell-Derived Extracellular Vesicle-Based Therapeutics for Inflammatory Lung Diseases

by Yu Fujita, Tsukasa Kadota, Jun Araya, Takahiro Ochiya, Kazuyoshi Kuwano
Published 2018-10-01

Extracellular Vesicles in Chronic Obstructive Pulmonary Disease

by Tsukasa Kadota, Yu Fujita, Yusuke Yoshioka, Jun Araya, Kazuyoshi Kuwano, Takahiro Ochiya
Published 2016-10-01

Suppression of autophagy by extracellular vesicles promotes myofibroblast differentiation in COPD pathogenesis

by Yu Fujita, Jun Araya, Saburo Ito, Kenji Kobayashi, Nobuyoshi Kosaka, Yusuke Yoshioka, Tsukasa Kadota, Hiromichi Hara, Kazuyoshi Kuwano, Takahiro Ochiya
Published 2015-11-01

Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk

by Tsukasa Kadota, Yu Fujita, Jun Araya, Naoaki Watanabe, Shota Fujimoto, Hironori Kawamoto, Shunsuke Minagawa, Hiromichi Hara, Takashi Ohtsuka, Yusuke Yamamoto, Kazuyoshi Kuwano, Takahiro Ochiya
Published 2021-08-01

Prostaglandin E-Major Urinary Metabolite (PGE-MUM) as a Tumor Marker for Lung Adenocarcinoma

by Hironori Kawamoto, Hiromichi Hara, Jun Araya, Akihiro Ichikawa, Yu Fujita, Hirofumi Utsumi, Mitsuo Hashimoto, Hiroshi Wakui, Shunsuke Minagawa, Takanori Numata, Seiji Arihiro, Tomokazu Matsuura, Mutsunori Fujiwara, Satoru Ito, Kazuyoshi Kuwano
Published 2019-06-01

Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth

by Yan Li, Lisa Elmén, Igor Segota, Yibo Xian, Roberto Tinoco, Yongmei Feng, Yu Fujita, Rafael R. Segura Muñoz, Robert Schmaltz, Linda M. Bradley, Amanda Ramer-Tait, Raphy Zarecki, Tao Long, Scott N. Peterson, Ze’ev A. Ronai
Published 2020-02-01

Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis

by Yu Fujita, Ali Khateb, Yan Li, Roberto Tinoco, Tongwu Zhang, Haggai Bar-Yoseph, Miguel A. Tam, Yehuda Chowers, Edmond Sabo, Shiran Gerassy-Vainberg, Elina Starosvetsky, Brian James, Kevin Brown, Shai S. Shen-Orr, Linda M. Bradley, Philippe A. Tessier, Ze’ev A. Ronai
Published 2018-09-01

Early prediction of COVID‐19 severity using extracellular vesicle COPB2

by Yu Fujita, Tokio Hoshina, Juntaro Matsuzaki, Yusuke Yoshioka, Tsukasa Kadota, Yusuke Hosaka, Shota Fujimoto, Hironori Kawamoto, Naoaki Watanabe, Kenji Sawaki, Yohei Sakamoto, Makiko Miyajima, Kwangyole Lee, Kazuhiko Nakaharai, Tetsuya Horino, Ryo Nakagawa, Jun Araya, Mitsuru Miyato, Masaki Yoshida, Kazuyoshi Kuwano, Takahiro Ochiya
Published 2021-06-01

Dietary cis-9, trans-11-conjugated linoleic acid reduces amyloid β-protein accumulation and upregulates anti-inflammatory cytokines in an Alzheimer’s disease mouse model

by Yu Fujita, Kuniyuki Kano, Shigenobu Kishino, Toshihiro Nagao, Xuefeng Shen, Chiharu Sato, Hatsune Hatakeyama, Yume Ota, Sho Niibori, Ayako Nomura, Kota Kikuchi, Wataru Yasuno, Sho Takatori, Kazunori Kikuchi, Yoshitake Sano, Taisuke Tomita, Toshiharu Suzuki, Junken Aoki, Kun Zou, Shunji Natori, Hiroto Komano
Published 2021-05-01

Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy

by Yusuke Kurita, Jun Araya, Shunsuke Minagawa, Hiromichi Hara, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Kazuya Tsubouchi, Nahoko Sato, Masahiro Yoshida, Kenji Kobayashi, Saburo Ito, Yu Fujita, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Yutaka Yoshii, Takeo Ishikawa, Takanori Numata, Yumi Kaneko, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama, Kazuyoshi Kuwano
Published 2017-06-01

The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors

by Ali Khateb, Anagha Deshpande, Yongmei Feng, Darren Finlay, Joo Sang Lee, Ikrame Lazar, Bertrand Fabre, Yan Li, Yu Fujita, Tongwu Zhang, Jun Yin, Ian Pass, Ido Livneh, Irmela Jeremias, Carol Burian, James R. Mason, Ronit Almog, Nurit Horesh, Yishai Ofran, Kevin Brown, Kristiina Vuori, Michael Jackson, Eytan Ruppin, Aniruddha J. Deshpande, Ze’ev A. Ronai
Published 2021-09-01

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 −/− mice

by Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian, Yu Fujita, Avinash Sahu, Raphy Zarecki, Kerrie Marie, Yongmei Feng, Ali Khateb, Dennie T. Frederick, Shiri K. Ashkenazi, Hyungsoo Kim, Eva Guijarro Perez, Chi-Ping Day, Rafael S. Segura Muñoz, Robert Schmaltz, Shibu Yooseph, Miguel A. Tam, Tongwu Zhang, Emily Avitan-Hersh, Lihi Tzur, Shoshana Roizman, Ilanit Boyango, Gil Bar-Sela, Amir Orian, Randal J. Kaufman, Marcus Bosenberg, Colin R. Goding, Bas Baaten, Mitchell P. Levesque, Reinhard Dummer, Kevin Brown, Glenn Merlino, Eytan Ruppin, Keith Flaherty, Amanda Ramer-Tait, Tao Long, Scott N. Peterson, Linda M. Bradley, Ze’ev A. Ronai
Published 2019-04-01