Geranylgeraniol Suppresses the Expression of IRAK1 and TRAF6 to Inhibit NFκB Activation in Lipopolysaccharide-Induced Inflammatory Responses in Human Macrophage-Like Cells

by Puspo E. Giriwono, Hitoshi Shirakawa, Yusuke Ohsaki, Shoko Sato, Yukihide Aoyama, Hsin-Jung Ho, Tomoko Goto, Michio Komai
Published 2019-05-01

<i>S</i>-allyl Cysteine Enhances Testosterone Production in Mice and Mouse Testis-Derived I-10 Cells

by Md Masud Rana, Kota Shiozawa, Katsuyuki Mukai, Katsuhiko Takayanagi, Koichi Eguchi, Halima Sultana, Yusuke Ohsaki, Michio Komai, Hitoshi Shirakawa
Published 2021-03-01

Effect of Vitamin K-Mediated PXR Activation on Drug-Metabolizing Gene Expression in Human Intestinal Carcinoma LS180 Cell Line

by Halima Sultana, Ayaka Kato, Ai Ohashi, Rie Takashima, Tomoko Katsurai, Shoko Sato, Masafumi Monma, Yusuke Ohsaki, Tomoko Goto, Michio Komai, Hitoshi Shirakawa
Published 2021-05-01

Supplementation with Fermented Rice Bran Attenuates Muscle Atrophy in a Diabetic Rat Model

by Tubagus Bahtiar Rusbana, Afifah Zahra Agista, Wahyu Dwi Saputra, Yusuke Ohsaki, Kouichi Watanabe, Ardy Ardiansyah, Slamet Budijanto, Takuya Koseki, Hisashi Aso, Michio Komai, Hitoshi Shirakawa
Published 2020-08-01

Fermented Rice Bran Supplementation Prevents the Development of Intestinal Fibrosis Due to DSS-Induced Inflammation in Mice

by Afifah Zahra Agista, Tubagus Bahtiar Rusbana, Jahidul Islam, Yusuke Ohsaki, Halima Sultana, Ryouta Hirakawa, Kouichi Watanabe, Tomonori Nochi, Ardiansyah, Slamet Budijanto, Suh-Ching Yang, Takuya Koseki, Hisashi Aso, Michio Komai, Hitoshi Shirakawa
Published 2021-05-01

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

by Koichi Kikuchi, Daisuke Saigusa, Yoshitomi Kanemitsu, Yotaro Matsumoto, Paxton Thanai, Naoto Suzuki, Koki Mise, Hiroaki Yamaguchi, Tomohiro Nakamura, Kei Asaji, Chikahisa Mukawa, Hiroki Tsukamoto, Toshihiro Sato, Yoshitsugu Oikawa, Tomoyuki Iwasaki, Yuji Oe, Tomoya Tsukimi, Noriko N. Fukuda, Hsin-Jung HO, Fumika Nanto-Hara, Jiro Ogura, Ritsumi Saito, Shizuko Nagao, Yusuke Ohsaki, Satoshi Shimada, Takehiro Suzuki, Takafumi Toyohara, Eikan Mishima, Hisato Shima, Yasutoshi Akiyama, Yukako Akiyama, Mariko Ichijo, Tetsuro Matsuhashi, Akihiro Matsuo, Yoshiaki Ogata, Ching-Chin Yang, Chitose Suzuki, Matthew C. Breeggemann, Jurgen Heymann, Miho Shimizu, Susumu Ogawa, Nobuyuki Takahashi, Takashi Suzuki, Yuji Owada, Shigeo Kure, Nariyasu Mano, Tomoyoshi Soga, Takashi Wada, Jeffrey B. Kopp, Shinji Fukuda, Atsushi Hozawa, Masayuki Yamamoto, Sadayoshi Ito, Jun Wada, Yoshihisa Tomioka, Takaaki Abe
Published 2019-04-01