Ultra-Deep Bisulfite Sequencing to Detect Specific DNA Methylation Patterns of Minor Cell Types in Heterogeneous Cell Populations: An Example of the Pituitary Tissue.

by Yoshikazu Arai, Hisho Fukukawa, Takanori Atozi, Shoma Matsumoto, Yutaka Hanazono, Hiroshi Nagashima, Jun Ohgane
Published 2016-01-01

Non-viral ex vivo genome-editing in mouse bona fide hematopoietic stem cells with CRISPR/Cas9

by Suvd Byambaa, Hideki Uosaki, Tsukasa Ohmori, Hiromasa Hara, Hitoshi Endo, Osamu Nureki, Yutaka Hanazono
Published 2021-03-01

MHC-matched induced pluripotent stem cells can attenuate cellular and humoral immune responses but are still susceptible to innate immunity in pigs.

by Yoshihisa Mizukami, Tomoyuki Abe, Hiroaki Shibata, Yukitoshi Makimura, Shuh-hei Fujishiro, Kimihide Yanase, Shuji Hishikawa, Eiji Kobayashi, Yutaka Hanazono
Published 2014-01-01

Variation in the Incidence of Teratomas after the Transplantation of Nonhuman Primate ES Cells into Immunodeficient Mice

by Yukiko Kishi, Yujiro Tanaka, Hiroaki Shibata, Shinichiro Nakamura, Koichi Takeuchi, Shigeo Masuda, Tamako Ikeda, Shin-Ichi Muramatsu, Yutaka Hanazono M.D., Ph.D.
Published 2008-09-01

CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice

by Tsukasa Ohmori, Yasumitsu Nagao, Hiroaki Mizukami, Asuka Sakata, Shin-ichi Muramatsu, Keiya Ozawa, Shin-ichi Tominaga, Yutaka Hanazono, Satoshi Nishimura, Osamu Nureki, Yoichi Sakata
Published 2017-06-01

ERas is Expressed in Primate Embryonic Stem Cells but not Related to Tumorigenesis

by Yujiro Tanaka, Tamako Ikeda, Yukiko Kishi, Shigeo Masuda, Hiroaki Shibata, Kengo Takeuchi, Makoto Komura, Tadashi Iwanaka, Shin-Ichi Muramatsu, Yasushi Kondo, Kazutoshi Takahashi, Shinya Yamanaka, Yutaka Hanazono M.D., Ph.D.
Published 2009-04-01

Generating porcine chimeras using inner cell mass cells and parthenogenetic preimplantation embryos.

by Kazuaki Nakano, Masahito Watanabe, Hitomi Matsunari, Taisuke Matsuda, Kasumi Honda, Miki Maehara, Takahiro Kanai, Gota Hayashida, Mirina Kobayashi, Momoko Kuramoto, Yoshikazu Arai, Kazuhiro Umeyama, Shuh-Hei Fujishiro, Yoshihisa Mizukami, Masaki Nagaya, Yutaka Hanazono, Hiroshi Nagashima
Published 2013-01-01

Correction: Generation of Interleukin-2 Receptor Gamma Gene Knockout Pigs from Somatic Cells Genetically Modified by Zinc Finger Nuclease-Encoding mRNA

by Masahito Watanabe, Kazuaki Nakano, Hitomi Matsunari, Taisuke Matsuda, Miki Maehara, Takahiro Kanai, Mirina Kobayashi, Yukina Matsumura, Rieko Sakai, Momoko Kuramoto, Gota Hayashida, Yoshinori Asano, Shuko Takayanagi, Yoshikazu Arai, Kazuhiro Umeyama, Masaki Nagaya, Yutaka Hanazono, Hiroshi Nagashima
Published 2014-01-01

Correction: Generation of Interleukin-2 Receptor Gamma Gene Knockout Pigs from Somatic Cells Genetically Modified by Zinc Finger Nuclease-Encoding mRNA.

by Masahito Watanabe, Kazuaki Nakano, Hitomi Matsunari, Taisuke Matsuda, Miki Maehara, Takahiro Kanai, Mirina Kobayashi, Yukina Matsumura, Rieko Sakai, Momoko Kuramoto, Gota Hayashida, Yoshinori Asano, Shuko Takayanagi, Yoshikazu Arai, Kazuhiro Umeyama, Masaki Nagaya, Yutaka Hanazono, Hiroshi Nagashima
Published 2014-01-01

Generation of interleukin-2 receptor gamma gene knockout pigs from somatic cells genetically modified by zinc finger nuclease-encoding mRNA.

by Masahito Watanabe, Kazuaki Nakano, Hitomi Matsunari, Taisuke Matsuda, Miki Maehara, Takahiro Kanai, Mirina Kobayashi, Yukina Matsumura, Rieko Sakai, Momoko Kuramoto, Gota Hayashida, Yoshinori Asano, Shuko Takayanagi, Yoshikazu Arai, Kazuhiro Umeyama, Masaki Nagaya, Yutaka Hanazono, Hiroshi Nagashima
Published 2013-01-01