Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors

by Yang Yang, Dongwei Kang, Laura A Nguyen, Zachary B Smithline, Christophe Pannecouque, Peng Zhan, Xinyong Liu, Thomas A Steitz
Published 2018-07-01

Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice.

by Zachary B Smithline, Anna S Nikonova, Harvey H Hensley, Kathy Q Cai, Brian L Egleston, David A Proia, Tamina Seeger-Nukpezah, Erica A Golemis
Published 2014-01-01