Comparative effects of oncogenic mutations G12C, G12V, G13D, and Q61H on local conformations and dynamics of K-Ras

by Sezen Vatansever, Burak Erman, Zeynep H. Gümüş
Published 2020-01-01

Resistance/Response Molecular Signature for Oral Tongue Squamous Cell Carcinoma

by Amritha Suresh, Muhil Vannan, Dhanya Kumaran, Zeynep H. Gümüs, Priya Sivadas, Elango Erode Murugaian, Vikram Kekatpure, Subramanian Iyer, Kumarasamy Thangaraj, Moni Abraham Kuriakose
Published 2012-01-01

Ancestral reconstruction reveals mechanisms of ERK regulatory evolution

by Dajun Sang, Sudarshan Pinglay, Rafal P Wiewiora, Myvizhi E Selvan, Hua Jane Lou, John D Chodera, Benjamin E Turk, Zeynep H Gümüş, Liam J Holt
Published 2019-08-01

A Machine Learning Approach for Hot-Spot Detection at Protein-Protein Interfaces

by Rita Melo, Robert Fieldhouse, André Melo, João D. G. Correia, Maria Natália D. S. Cordeiro, Zeynep H. Gümüş, Joaquim Costa, Alexandre M. J. J. Bonvin, Irina S. Moreira
Published 2016-07-01

SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots

by Irina S. Moreira, Panagiotis I. Koukos, Rita Melo, Jose G. Almeida, Antonio J. Preto, Joerg Schaarschmidt, Mikael Trellet, Zeynep H. Gümüş, Joaquim Costa, Alexandre M. J. J. Bonvin
Published 2017-08-01

Ancestry-specific predisposing germline variants in cancer

by Ninad Oak, Andrew D. Cherniack, R. Jay Mashl, TCGA Analysis Network, Fred R. Hirsch, Li Ding, Rameen Beroukhim, Zeynep H. Gümüş, Sharon E. Plon, Kuan-lin Huang
Published 2020-05-01

Dynamical Rearrangement of Human Epidermal Growth Factor Receptor 2 upon Antibody Binding: Effects on the Dimerization

by Pedro R. Magalhães, Miguel Machuqueiro, José G. Almeida, André Melo, M. Natália D. S. Cordeiro, Sandra Cabo Verde, Zeynep H. Gümüş, Irina S. Moreira, João D. G. Correia, Rita Melo
Published 2019-11-01

Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection

by Daniela Michlmayr, Eun-Young Kim, Adeeb H. Rahman, Rohit Raghunathan, Seunghee Kim-Schulze, Yan Che, Selim Kalayci, Zeynep H. Gümüş, Guillermina Kuan, Angel Balmaseda, Andrew Kasarskis, Steven M. Wolinsky, Mayte Suaréz-Fariñas, Eva Harris
Published 2020-04-01