A_2B Adenosine Receptor and Cancer

by Zhan-Guo Gao, Kenneth A. Jacobson
Published 2019-10-01

Purinergic Signaling in Mast Cell Degranulation and Asthma

by Zhan-Guo Gao, Kenneth A. Jacobson
Published 2017-12-01

Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development

by Kenneth A. Jacobson, Dilip K. Tosh, Shanu Jain, Zhan-Guo Gao
Published 2019-03-01

Allosteric Antagonism of the A_2A Adenosine Receptor by a Series of Bitopic Ligands

by Zhan-Guo Gao, Kiran S. Toti, Ryan Campbell, R. Rama Suresh, Huijun Yang, Kenneth A. Jacobson
Published 2020-05-01

Limits of ligand selectivity from docking to models: in silico screening for A(1) adenosine receptor antagonists.

by Peter Kolb, Khai Phan, Zhan-Guo Gao, Adam C Marko, Andrej Sali, Kenneth A Jacobson
Published 2012-01-01

John Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y Receptors

by Kenneth A. Jacobson, Zhan-Guo Gao, Silvia Paoletta, Evgeny Kiselev, Saibal Chakraborty, P. Suresh Jayasekara, Ramachandran Balasubramanian, Dilip K. Tosh
Published 2015-01-01

Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A 2A adenosine receptor binding site

by Pierre Matricon, Anirudh Ranganathan, Eugene Warnick, Zhan-Guo Gao, Axel Rudling, Catia Lambertucci, Gabriella Marucci, Aitakin Ezzati, Mariama Jaiteh, Diego Dal Ben, Kenneth A. Jacobson, Jens Carlsson
Published 2017-07-01

Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists

by Dilip K. Tosh, Antonella Ciancetta, Philip Mannes, Eugene Warnick, Aaron Janowsky, Amy J. Eshleman, Elizabeth Gizewski, Tarsis F. Brust, Laura M. Bohn, John A. Auchampach, Zhan-Guo Gao, Kenneth A. Jacobson
Published 2018-10-01