High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation

by Mateusz Legut, Zharko Daniloski, Xinhe Xue, Dayna McKenzie, Xinyi Guo, Hans-Hermann Wessels, Neville E. Sanjana
Published 2020-03-01

Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus

by Silva Kasela, Zharko Daniloski, Sailalitha Bollepalli, Tristan X. Jordan, Benjamin R. tenOever, Neville E. Sanjana, Tuuli Lappalainen
Published 2021-08-01

The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types

by Zharko Daniloski, Tristan X Jordan, Juliana K Ilmain, Xinyi Guo, Gira Bhabha, Benjamin R tenOever, Neville E Sanjana
Published 2021-02-01

An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation?

by Margot Brandt, Sarah Kim-Hellmuth, Marcello Ziosi, Alper Gokden, Aaron Wolman, Nora Lam, Yocelyn Recinos, Zharko Daniloski, John A Morris, Veit Hornung, Johannes Schumacher, Tuuli Lappalainen
Published 2021-07-01