Detection of Side Chain Rearrangements Mediating the Motions of Transmembrane Helices in Molecular Dynamics Simulations of G Protein-Coupled Receptors

by Zied Gaieb, Dimitrios Morikis
Published 2017-01-01

An Analysis of Proteochemometric and Conformal Prediction Machine Learning Protein-Ligand Binding Affinity Models

by Conor Parks, Zied Gaieb, Rommie E. Amaro
Published 2020-06-01

Comparison of commonly used solid tumor targeted gene sequencing panels for estimating tumor mutation burden shows analytical and prognostic concordance within the cancer genome at...

by Nicholas Bevins, Shulei Sun, Zied Gaieb, John A Thorson, Sarah S Murray
Published 2020-06-01

Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors

by Manoj K Rathinaswamy, Zied Gaieb, Kaelin D Fleming, Chiara Borsari, Noah J Harris, Brandon E Moeller, Matthias P Wymann, Rommie E Amaro, John E Burke
Published 2021-03-01

Role of Electrostatic Hotspots in the Selectivity of Complement Control Proteins Toward Human and Bovine Complement Inhibition

by Yogesh B. Narkhede, Avneesh K. Gautam, Rohaine V. Hsu, Wilson Rodriguez, Nehemiah T. Zewde, Reed E. S. Harrison, Pablo R. Arantes, Zied Gaieb, Ronald D. Gorham, Chris Kieslich, Chris Kieslich, Dimitrios Morikis, Arvind Sahu, Giulia Palermo, Giulia Palermo
Published 2021-03-01