Blockage of NLRP3 inflammasome activation ameliorates acute inflammatory injury and long-term cognitive impairment induced by necrotizing enterocolitis in mice

by Fangxinxing Zhu, Lingyu Wang, Zizhen Gong, Yanyan Wang, Yanhong Gao, Wei Cai, Jin Wu
Published 2021-03-01

N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Mitigates Experimental Colitis Through Inhibition of Intestinal Mucosal Inflammatory Responses via MEK-ERK Signaling

by Yingying Shi, Mingxia Zhou, Junkai Yan, Zizhen Gong, Jin Wu, Yuanwen Chen, Yingwei Chen
Published 2020-05-01

Deoxycholic acid triggers NLRP3 inflammasome activation and aggravates DSS-induced colitis in mice

by Jin Wu, Shengnan Zhao, Zizhen Gong, Jiefei Zhou, Chunyan Tian, Yanhong Gao, Congfeng Xu, Yingwei Chen, Wei Cai
Published 2016-11-01

Deoxycholic Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Exacerbates DSS-Induced Colitis through Promoting Cathepsin B Release

by Shengnan Zhao, Zizhen Gong, Xixi Du, Chunyan Tian, Lingyu Wang, Jiefei Zhou, Congfeng Xu, Yingwei Chen, Wei Cai, Jin Wu
Published 2018-01-01

Gut microbial bile acid metabolite skews macrophage polarization and contributes to high-fat diet-induced colonic inflammation

by Lingyu Wang, Zizhen Gong, Xiuyuan Zhang, Fangxinxing Zhu, Yuchen Liu, Chaozhi Jin, Xixi Du, Congfeng Xu, Yingwei Chen, Wei Cai, Chunyan Tian, Jin Wu
Published 2020-11-01