The Physiological Functions of the Amyloid Precursor Protein Gene Family

The amyloid precursor protein APP plays a key role in the pathogenesis of Alzheimer's disease (AD), as proteolytical cleavage of APP gives rise to the Aß peptide which is deposited in the brains of Alzheimer patients. Despite this, our knowledge of the normal cell biological and physiological f...

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Bibliographic Details
Format: eBook
Language:English
Published: Frontiers Media SA 2017
Series:Frontiers Research Topics
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