Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients

Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients

Certain proteins have demonstrated proficient human immunodeficiency virus (HIV-1) life cycle disturbance. Recently, the ankyrin repeat protein targeting the HIV-1 capsid, Ank<sup>GAG</sup>1D4, showed a negative effect on the viral assembly of the HIV-1<sub>NL4-3</sub> labora...

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Bibliographic Details
Main Authors: Supachai Sakkhachornphop, Sudarat Hadpech, Tanchanok Wisitponchai, Chansunee Panto, Doungnapa Kantamala, Utaiwan Utaipat, Jutarat Praparattanapan, Wilai Kotarathitithum, Sineenart Taejaroenkul, Umpa Yasamut, Koollawat Chupradit, Sutpirat Moonmuang, Vannajan Sanghiran Lee, Khuanchai Suparatpinyo, Chatchai Tayapiwatana
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Viruses
Subjects:
HIV-1
Gag polyprotein
virus assembly inhibitor
ankyrin
protein therapy
Online Access:https://www.mdpi.com/1999-4915/10/11/625

Internet

https://www.mdpi.com/1999-4915/10/11/625

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