All the Same? The Secret Life of Prion Strains within Their Target Cells
Prions are infectious β-sheet-rich protein aggregates composed of misfolded prion protein (PrP<sup>Sc</sup>) that do not possess coding nucleic acid. Prions replicate by recruiting and converting normal cellular PrP<sup>C</sup> into infectious isoforms. In the same h...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-04-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/11/4/334 |