HBA-DEALS: accurate and simultaneous identification of differential expression and splicing using hierarchical Bayesian analysis

HBA-DEALS: accurate and simultaneous identification of differential expression and splicing using hierarchical Bayesian analysis

Abstract We present Hierarchical Bayesian Analysis of Differential Expression and ALternative Splicing (HBA-DEALS), which simultaneously characterizes differential expression and splicing in cohorts. HBA-DEALS attains state of the art or better performance for both expression and splicing and allows...

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Bibliographic Details
Main Authors: Guy Karlebach, Peter Hansen, Diogo FT Veiga, Robin Steinhaus, Daniel Danis, Sheng Li, Olga Anczukow, Peter N Robinson
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Genome Biology
Subjects:
Differential expression
Alternative splicing
Transcription
Online Access:http://link.springer.com/article/10.1186/s13059-020-02072-6

Internet

http://link.springer.com/article/10.1186/s13059-020-02072-6

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