Increased iron sequestration in alveolar macrophages in chronic obstructive pulmonary disease.

Increased iron sequestration in alveolar macrophages in chronic obstructive pulmonary disease.

Free iron in lung can cause the generation of reactive oxygen species, an important factor in chronic obstructive pulmonary disease (COPD) pathogenesis. Iron accumulation has been implicated in oxidative stress in other diseases, such as Alzheimer's and Parkinson's diseases, but little is...

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Main Authors: Quentin Philippot, Gaëtan Deslée, Tracy L Adair-Kirk, Jason C Woods, Derek Byers, Susan Conradi, Sandra Dury, Jeanne Marie Perotin, François Lebargy, Christelle Cassan, Richard Le Naour, Michael J Holtzman, Richard A Pierce
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4006868?pdf=render

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http://europepmc.org/articles/PMC4006868?pdf=render

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