Extracellular vesicles derived from mesenchymal stromal cells mitigate intestinal toxicity in a mouse model of acute radiation syndrome

Extracellular vesicles derived from mesenchymal stromal cells mitigate intestinal toxicity in a mouse model of acute radiation syndrome

Abstract Background Human exposure to high doses of radiation resulting in acute radiation syndrome and death can rapidly escalate to a mass casualty catastrophe in the event of nuclear accidents or terrorism. The primary reason is that there is presently no effective treatment option, especially fo...

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Bibliographic Details
Main Authors: Alison Accarie, Bruno l’Homme, Mohamed Amine Benadjaoud, Sai Kiang Lim, Chandan Guha, Marc Benderitter, Radia Tamarat, Alexandra Sémont
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Acute radiation syndrome
Gastrointestinal syndrome
Intestinal epithelial barrier
Medical countermeasures
Mesenchymal stromal cell-derived extracellular vesicles
Online Access:http://link.springer.com/article/10.1186/s13287-020-01887-1

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http://link.springer.com/article/10.1186/s13287-020-01887-1

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