Integrated Microarray and RNAseq Transcriptomic Analysis of Retinal Pigment Epithelium/Choroid in Age-Related Macular Degeneration

Integrated Microarray and RNAseq Transcriptomic Analysis of Retinal Pigment Epithelium/Choroid in Age-Related Macular Degeneration

We report for the first time an integrated transcriptomic analysis of RPE/choroid dysfunction in AMD (mixed stages) based on combining data from publicly available microarray (GSE29801) and RNAseq (GSE135092) datasets aimed at increasing the ability and power of detection of differentially expressed...

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Bibliographic Details
Main Authors: Dhanach Dhirachaikulpanich, Xin Li, Louise F. Porter, Luminita Paraoan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
age-related macular degeneration
retinal pigment epithelium
neurodegeneration
transcriptome
neuroactive ligand-receptor
extracellular matrix
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00808/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00808/full

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