Heparan sulfate: Resilience factor and therapeutic target for cocaine abuse

Abstract Substance abuse is a pressing problem with few therapeutic options. The identification of addiction resilience factors is a potential strategy to identify new mechanisms that can be targeted therapeutically. Heparan sulfate (HS) is a linear sulfated polysaccharide that is a component of the...

Full description

Bibliographic Details
Main Authors: Jihuan Chen, Tomoya Kawamura, Manveen K. Sethi, Joseph Zaia, Vez Repunte-Canonigo, Pietro Paolo Sanna
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-13960-6