Inhibitor of neuronal nitric oxide synthase improves gas exchange in ventilator-induced lung injury after pneumonectomy

Inhibitor of neuronal nitric oxide synthase improves gas exchange in ventilator-induced lung injury after pneumonectomy

<p>Abstract</p> <p>Background</p> <p>Mechanical ventilation with high tidal volumes may cause ventilator-induced lung injury (VILI) and enhanced generation of nitric oxide (NO). We demonstrated in sheep that pneumonectomy followed by injurious ventilation promotes pulmo...

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Bibliographic Details
Main Authors: Suborov Evgeny V, Smetkin Alexey A, Kondratiev Timofey V, Valkov Andrey Y, Kuzkov Vsevolod V, Kirov Mikhail Y, Bjertnaes Lars J
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Anesthesiology
Subjects:
Pneumonectomy
Mechanical ventilation
nNOS
Pulmonary edema
Sheep
Nitric oxide
Ventilator-induced lung injury
7-nitroindazole
Online Access:http://www.biomedcentral.com/1471-2253/12/10

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http://www.biomedcentral.com/1471-2253/12/10

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