Early phase 2 trial of TAS‐205 in patients with Duchenne muscular dystrophy

Early phase 2 trial of TAS‐205 in patients with Duchenne muscular dystrophy

Abstract Objective Duchenne muscular dystrophy (DMD) is a progressive muscular disease characterized by chronic cycles of inflammatory and necrotic processes. Prostaglandin D2 (PGD2) is produced by hematopoietic PGD synthase (HPGDS), which is pathologically implicated in muscle necrosis. This random...

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Bibliographic Details
Main Authors: Hirofumi Komaki, Yoshihiro Maegaki, Tsuyoshi Matsumura, Kazuhiro Shiraishi, Hiroyuki Awano, Akinori Nakamura, Satoru Kinoshita, Katsuhisa Ogata, Keiko Ishigaki, Shinji Saitoh, Michinori Funato, Satoshi Kuru, Takahiro Nakayama, Yasuyuki Iwata, Hiroyuki Yajima, Shin’ichi Takeda
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.50978

Internet

https://doi.org/10.1002/acn3.50978

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