Melatonin and Docosahexaenoic Acid Decrease Proliferation of PNT1A Prostate Benign Cells via Modulation of Mitochondrial Bioenergetics and ROS Production

Prostate cancer development has been associated with changes in mitochondrial activity and reactive oxygen species (ROS) production. Melatonin (MLT) and docosahexaenoic acid (DHA) have properties to modulate both, but their protective role, mainly at early stages of prostate cancer, remains unclear....

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Bibliographic Details
Main Authors: Guilherme H. Tamarindo, Daniele L. Ribeiro, Marina G. Gobbo, Luiz H. A. Guerra, Paula Rahal, Sebastião R. Taboga, Fernanda R. Gadelha, Rejane M. Góes
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/5080798