Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation

<p>Abstract</p> <p>Background</p> <p>Manipulating apoptotic resistance represents an important strategy for the treatment of hormone refractory prostate cancer. We hypothesised that the Inhibitor of Apoptosis (IAP) Proteins may be mediating this resistance and knockdown...

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Bibliographic Details
Main Authors: Dowling Catherine, Gill Catherine, O'Neill Amanda J, Watson R William G
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/39