Aromatic inhibitors derived from ammonia-pretreated lignocellulose hinder bacterial ethanologenesis by activating regulatory circuits controlling inhibitor efflux and detoxification

Aromatic inhibitors derived from ammonia-pretreated lignocellulose hinder bacterial ethanologenesis by activating regulatory circuits controlling inhibitor efflux and detoxification

Efficient microbial conversion of lignocellulosic hydrolysates to biofuels is a key barrier to the economically viable deployment of lignocellulosic biofuels. A chief contributor to this barrier is the impact on microbial processes and energy metabolism of lignocellulose-derived inhibitors, includin...

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Bibliographic Details
Main Authors: David H. Keating, Yaoping Zhang, Irene M. Ong, Sean McIlwain, Eduardo H. Morales, Jeffrey A. Grass, Mary Tremaine, William Bothfeld, Alan Higbee, Arne Ulbrich, Allison J. Balloon, Michael S. Westphall, Josh Aldrich, Mary S. Lipton, Joonhoon Kim, Oleg V. Moskvin, Yury V. Bukhman, Joshua J. Coon, Patricia J. Kiley, Donna M. Bates, Robert Landick
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
lignocellulosic hydrolysate
aromatic inhibitors
transcriptomics
RNAseq
proteomics
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2014.00402/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2014.00402/full

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