Extracellular Matrix Remodeling in the Retina and Optic Nerve of a Novel Glaucoma Mouse Model

Extracellular Matrix Remodeling in the Retina and Optic Nerve of a Novel Glaucoma Mouse Model

Glaucoma is a neurodegenerative disease that is characterized by the loss of retinal ganglion cells (RGC) and optic nerve fibers. Increased age and intraocular pressure (IOP) elevation are the main risk factors for developing glaucoma. Mice that are heterozygous (HET) for the mega-karyocyte protein...

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Bibliographic Details
Main Authors: Jacqueline Reinhard, Susanne Wiemann, Sebastian Hildebrandt, Andreas Faissner
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biology
Subjects:
extracellular matrix
fibronectin
glaucoma
glycoproteins
intraocular pressure
laminins
Online Access:https://www.mdpi.com/2079-7737/10/3/169

Internet

https://www.mdpi.com/2079-7737/10/3/169

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