HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration

Oxidative stress-mediated retinal pigment epithelium (RPE) degeneration plays a vital role in retinal degeneration with irreversible visual impairment, most notably in age-related macular degeneration (AMD), but a key pathogenic factor and the targeted medical control remain controversial and unclea...

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Bibliographic Details
Main Authors: Zhimin Tang, Yahan Ju, Xiaochan Dai, Ni Ni, Yan Liu, Dandan Zhang, Huiqin Gao, Hao Sun, Jing Zhang, Ping Gu
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721001191