EGFR signaling promotes β-cell proliferation and survivin expression during pregnancy.

Placental lactogen (PL) induced serotonergic signaling is essential for gestational β-cell mass expansion. We have previously shown that intact Epidermal growth factor -receptor (EGFR) function is a crucial component of this pathway. We now explored more specifically the link between EGFR and pregna...

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Bibliographic Details
Main Authors: Elina Hakonen, Jarkko Ustinov, Jaan Palgi, Päivi J Miettinen, Timo Otonkoski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24695557/pdf/?tool=EBI