H-Ferritin Affects Cisplatin-Induced Cytotoxicity in Ovarian Cancer Cells through the Modulation of ROS

H-Ferritin Affects Cisplatin-Induced Cytotoxicity in Ovarian Cancer Cells through the Modulation of ROS

Reactive oxygen species (ROS) mediates cisplatin-induced cytotoxicity in tumor cells. However, when cisplatin-induced ROS do not reach cytotoxic levels, cancer cells may develop chemoresistance. This phenomenon can be attributed to the inherited high expression of antioxidant protein network. H-Ferr...

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Bibliographic Details
Main Authors: Alessandro Salatino, Ilenia Aversa, Anna Martina Battaglia, Alessandro Sacco, Anna Di Vito, Gianluca Santamaria, Roberta Chirillo, Pierangelo Veltri, Giuseppe Tradigo, Annalisa Di Cello, Roberta Venturella, Flavia Biamonte, Francesco Costanzo
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/3461251

Internet

http://dx.doi.org/10.1155/2019/3461251

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