Apoptosis-promoting properties of miR-3074-5p in MC3T3-E1 cells under iron overload conditions

Apoptosis-promoting properties of miR-3074-5p in MC3T3-E1 cells under iron overload conditions

Abstract Background Iron overload can promote the development of osteoporosis by inducing apoptosis in osteoblasts. However, the mechanism by which miRNAs regulate apoptosis in osteoblasts under iron overload has not been elucidated. Method The miRNA expression profile in MC3T3-E1 cells under iron o...

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Bibliographic Details
Main Authors: Yi Feng, Pei-Yan He, Wei-Dong Kong, Wan-Jing Cen, Peng-Lin Wang, Chang Liu, Wu Zhang, Shu-Shu Li, Jian-Wei Jiang
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cellular & Molecular Biology Letters
Subjects:
Iron overload
Osteoporosis
Apoptosis
MC3T3-E1 cells
miRNA-3074-5p
Online Access:https://doi.org/10.1186/s11658-021-00281-w

Internet

https://doi.org/10.1186/s11658-021-00281-w

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