Overexpression of HOTAIR leads to radioresistance of human cervical cancer via promoting HIF-1α expression

Overexpression of HOTAIR leads to radioresistance of human cervical cancer via promoting HIF-1α expression

Abstract Background HOTAIR was known to enhance radioresistance in several cancers. However, the function of HOTAIR on radioresistance involving the regulation of HIF-1α in cervical cancer has not been reported. Methods BALB/c nude mice were injected subcutaneously with HeLa cells and irradiated by...

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Bibliographic Details
Main Authors: Ning Li, Dan-dan Meng, Ling Gao, Yue Xu, Pei-jie Liu, Yong-wei Tian, Zhen-ying Yi, Yan Zhang, Xiao-jing Tie, Zhi-qiao Xu
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Radiation Oncology
Subjects:
Radiotherapy
Cervical cancer
HOTAIR
HIF-1α
Cell apoptosis
Online Access:http://link.springer.com/article/10.1186/s13014-018-1153-4

Internet

http://link.springer.com/article/10.1186/s13014-018-1153-4

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