A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography
Determining optimal conditions for the production of well diffracting crystals is a key step in every biocrystallography project. Here, a microfluidic device is described that enables the production of crystals by counter-diffusion and their direct on-chip analysis by serial crystallography at room...
Main Authors: | Raphaël de Wijn, Oliver Hennig, Jennifer Roche, Sylvain Engilberge, Kevin Rollet, Pablo Fernandez-Millan, Karl Brillet, Heike Betat, Mario Mörl, Alain Roussel, Eric Girard, Christoph Mueller-Dieckmann, Gavin C. Fox, Vincent Olieric, José A. Gavira, Bernard Lorber, Claude Sauter |
---|---|
Format: | Article |
Language: | English |
Published: |
International Union of Crystallography
2019-05-01
|
Series: | IUCrJ |
Subjects: | |
Online Access: | http://scripts.iucr.org/cgi-bin/paper?S2052252519003622 |
Similar Items
-
Experimental phase determination with selenomethionine or mercury-derivatization in serial femtosecond crystallography
by: Keitaro Yamashita, et al.
Published: (2017-09-01) -
The Neutron Macromolecular Crystallography Instruments at Oak Ridge National Laboratory: Advances, Challenges, and Opportunities
by: Flora Meilleur, et al.
Published: (2018-10-01) -
Monitoring the Production of High Diffraction-Quality Crystals of Two Enzymes in Real Time Using In Situ Dynamic Light Scattering
by: Raphaël de Wijn, et al.
Published: (2020-01-01) -
Functional dendrimers: synthesis and applications.
Published: (1996) -
Life In Motion: Visualizing Biomacromolecules By Time-Resolved Serial Femtosecond Crystallography
Published: (2018)